Evidence map›Paper›PMID 26048045›Full record

ArticleBMC complementary and alternative medicine2015

Frequency and co-prescription pattern of Chinese herbal products for hypertension in Taiwan: a Cohort study.

Pei-Rung Yang, Wei-Tai Shih, Yen-Hua Chu, Pau-Chung Chen, Ching-Yuan Wu

Abstract read
In one paragraph

Article in BMC complementary and alternative medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Trends in Coprescription Among Taiwanese Children from 2002 to 2012.Journal of multidisciplinary healthcare · 2023
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Prescription of RadixFrontiers in pharmacology · 2021
    Article
  11. Review
  12. Traditional Chinese Medicine for Essential Hypertension: A Clinical Evidence Map.Evidence-based complementary and alternative medicine : eCAM · 2020
    Article
  13. Pregnant women's use and attitude toward herbal, vitamin, and mineral supplements in an academic tertiary care center, Riyadh, Saudi Arabia.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2019
    Article
  14. Article
  15. Treatment of Urolithiasis with Medicinal PlantEvidence-based complementary and alternative medicine : eCAM · 2018
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Dysfunction of the thymus in mice with hypertension.Experimental and therapeutic medicine · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pei-Rung YangDepartment of Traditional Chinese Medicine, Chang Gung Memorial Hospital, No.6, W. Sec., Jiapu RD., Puzi City, Chia-Yi County, 61363, Taiwan.
Wei-Tai ShihDepartment of Traditional Chinese Medicine, Chang Gung Memorial Hospital, No.6, W. Sec., Jiapu RD., Puzi City, Chia-Yi County, 61363, Taiwan.
Yen-Hua ChuDepartment of Traditional Chinese Medicine, Chang Gung Memorial Hospital, No.6, W. Sec., Jiapu RD., Puzi City, Chia-Yi County, 61363, Taiwan.
Pau-Chung ChenInstitute of Occupational Medicine and Industrial Hygiene, National Taiwan University College of Public Health, Taipei, 10055, Taiwan.
Ching-Yuan WuDepartment of Traditional Chinese Medicine, Chang Gung Memorial Hospital, No.6, W. Sec., Jiapu RD., Puzi City, Chia-Yi County, 61363, Taiwan. smbepigwu77@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChinese herbal products (CHPs) have been frequently used among patients with chronic diseases including hypertension; however, the co-prescription pattern of herbal formulae and single herbs remain uncharacterized. Thus, this large-scale pharmacoepidemiological study evaluated the frequency and co-prescription pattern of CHPs for treating hypertension in Taiwan from 2003 to 2009.

methodsThe database of traditional Chinese medicine (TCM) outpatient claims was obtained from the National Health Insurance in Taiwan. Patients with hypertension during study period were defined according to diagnostic codes in the International Classification of Disease Ninth Revision, Clinical Modification. The frequencies and percentages of herbal formula and single herb prescriptions for hypertension were analyzed. We also applied association rules to evaluate the CHPs co-prescription patterns.

resultsThe hypertension cohort included 154,083 patients, 123,240 patients of which (approximately 80 %) had used TCM at least once. In total, 81,582 visits involving CHP prescriptions were hypertension related; Tian-Ma-Gou-Teng-Yin and Dan Shen (Radix Salvia Miltiorrhizae) were the most frequently prescribed herbal formula and single herb, respectively, for treating hypertension.

conclusionsThis study elucidated the utilization pattern of CHPs for treating hypertension. Future studies on the efficacy and safety of these CHPs and on drug-herb interactions are warranted.

Indexed as

Medicine, Chinese TraditionalPhytotherapyPrescriptionsProfessional PracticeCohort StudiesDatabases, FactualDrugs, Chinese HerbalFemaleHumansHypertensionMaleMiddle AgedNational Health ProgramsOutpatientsSalvia miltiorrhizaTaiwandan-shen root extractDrugs, Chinese Herbalgou-tengtianma gouteng

Identifiers

PMID26048045
PMCPMC4457084

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.