Evidence map›Paper›PMID 26047943›Full record

ArticleInternational journal of clinical pharmacy2015

Potential drug-related problems detected by electronic expert support system: physicians' views on clinical relevance.

Tora Hammar, Bodil Lidström, Göran Petersson, Yngve Gustafson, Birgit Eiermann

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Article in International journal of clinical pharmacy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
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13citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Tora HammarDepartment of Medicine and Optometry, eHealth Institute, Linnaeus University, 391 82, Kalmar, Sweden. tora.hammar@lnu.se.
Bodil LidströmSwedish eHealth Agency, Stockholm, Sweden.
Göran PeterssonDepartment of Medicine and Optometry, eHealth Institute, Linnaeus University, 391 82, Kalmar, Sweden.
Yngve GustafsonDivision of Geriatric Medicine, Department of Community Medicine and Rehabilitation, Umeå University, Umeå, Sweden.
Birgit EiermannSwedish eHealth Agency, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDrug-related problems cause suffering for patients and substantial costs. Multi-dose drug dispensing is a service in which patients receive their medication packed in bags with one unit for each dose occasion. The electronic expert support system (EES) is a clinical decision support system that provides alerts if potential drug-related problems are detected among a patients' current prescriptions, including drug-drug interactions, therapy duplications, high doses, drug-disease interactions, drug gender warnings, and inappropriate drugs and doses for geriatric or pediatric patients.

objectiveThe aim of the study was to explore physicians' views on the clinical relevance of alerts provided by EES. Furthermore we investigated if physicians performed any changes in drug treatment following the alerts and if there were any differences in perceived relevance and performed changes between different types of alerts and drugs.

settingTwo geriatric clinics and three primary care units in Sweden.

methodPrescribed medications for patients (n = 254) with multi-dose drug dispensing were analyzed for potential drug-related problems using EES. For each alert, a physician assessed clinical relevance and indicated any intended action. A total of 15 physicians took part in the study. Changes in drug treatment following the alerts were later measured. The relationship between variables was analyzed using Chi square test.

main outcome measurePhysicians' perceived clinical relevance of each alert, and changes in drug treatment following the alerts.

resultsPhysicians perceived 68% (502/740) of EES alerts as clinically relevant and 11% of all alerts were followed by a change in drug treatment. Clinical relevance and likelihood to make changes in drug treatment was related to the alert category and substances involved in the alert.

conclusionIn most patients with multi-dose drug dispensing, EES detected potential drug-related problems, with the majority of the alerts regarded as clinically relevant and some followed by measurable changes in drug treatment.

Indexed as

Attitude of Health PersonnelMedical Order Entry SystemsAgedAged, 80 and overFemaleHumansMaleMedication ErrorsPhysiciansAlertsClinical decision support systemsDrug-related problemsGeriatric patientsMulti-dose drug dispensingRelevanceSweden

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.