Evidence map›Paper›PMID 26047939›Full record

ArticleCardiovascular diabetology2015

Association of insulin resistance and coronary artery remodeling: an intravascular ultrasound study.

Sang-Hoon Kim, Jae-Youn Moon, Yeong Min Lim, Kyung Ho Kim, Woo-In Yang, Jung-Hoon Sung, Seung Min Yoo, In Jai Kim, Sang-Wook Lim, Dong-Hun Cha and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiovascular diabetology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Frontiers in endocrinology · 2017
    Article
  10. Stabilization of high-risk plaques.Cardiovascular diagnosis and therapy · 2016
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sang-Hoon KimDepartment of Cardiology, CHA Bundang Medical Center, CHA University, Seongnam, South Korea.
Jae-Youn MoonDepartment of Cardiology, CHA Bundang Medical Center, CHA University, Seongnam, South Korea. answod77@naver.com.
Yeong Min LimDepartment of Cardiology, CHA Bundang Medical Center, CHA University, Seongnam, South Korea.
Kyung Ho KimDepartment of Cardiology, CHA Bundang Medical Center, CHA University, Seongnam, South Korea.
Woo-In YangDepartment of Cardiology, CHA Bundang Medical Center, CHA University, Seongnam, South Korea.
Jung-Hoon SungDepartment of Cardiology, CHA Bundang Medical Center, CHA University, Seongnam, South Korea.
Seung Min YooDepartment of Diagnostic Radiology, CHA Bundang Medical Center, CHA University, Seongnam, South Korea.
In Jai KimDepartment of Cardiology, CHA Bundang Medical Center, CHA University, Seongnam, South Korea.
Sang-Wook LimDepartment of Cardiology, CHA Bundang Medical Center, CHA University, Seongnam, South Korea.
Dong-Hun ChaDepartment of Cardiology, CHA Bundang Medical Center, CHA University, Seongnam, South Korea.
Seung-Yun ChoDepartment of Cardiology, CHA Bundang Medical Center, CHA University, Seongnam, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are few studies that investigated the correlation between insulin resistance (IR) and the coronary artery remodeling. The aim of the study is to investigate the association of IR measured by homeostasis model assessment of insulin resistance (HOMA-IR) and coronary artery remodeling evaluated by intravascular ultrasound (IVUS).

methodsA total of 298 consecutive patients who received percutaneous coronary interventions under IVUS guidance were retrospectively enrolled. The value of HOMA-IR more than 2.5 was considered as IR positive. Metabolic syndrome was classified according to NCEP ATP III guidelines. The remodeling index was defined as the ratio of the external elastic membrane (EEM) area at the lesion site to the EEM area at the proximal reference site.

resultsA total of 369 lesions were analyzed (161 lesions in HOMA-IR positive and 208 lesions in HOMA-IR negative). Remodeling index was significantly higher in the HOMA-IR positive group compared with the negative group (HOMA-IR positive vs. negative: 1.074 ± 0.109 vs. 1.042 ± 0.131, p = 0.013). There was a significant positive correlation between remodeling index and HOMA-IR (p = 0.010). Analysis of HOMA-IR according to remodeling groups showed increasing tendency of HOMA-IR, and it was statistically significant (p = 0.045). Multivariate analysis revealed that only HOMA-IR was an independent predictor of remodeling index (r = 0.166, p = 0.018).

conclusionIncreased IR estimated by HOMA-IR was significantly associated with a higher remodeling index and positive coronary artery remodeling.

Indexed as

Insulin ResistanceVascular RemodelingAgedCohort StudiesCoronary Artery DiseaseCoronary VesselsFemaleHumansMaleMetabolic SyndromeMiddle AgedMultivariate AnalysisPercutaneous Coronary InterventionRetrospective StudiesStentsSurgery, Computer-Assisted

Identifiers

PMID26047939
PMCPMC4472609

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.