ReviewNeuroscience2015
Neural control of movement stability: Lessons from studies of neurological patients.
Review in Neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
68 citing papers in PubMed, 1 synthesis or guideline pooled it, 164 citations in OpenAlex.
- Evidence of Animal-Assisted Therapy in Neurological Diseases in Adults: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Preparatory use of neurodynamics to enhance upper limb function in patients with acquired brain injury: a randomized controlled trial.Scientific reports · 2025Trial
- Dopaminergic modulation of multi-muscle synergies in postural tasks performed by patients with Parkinson's disease.Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology · 2017Trial
- Effects of first-step constraints on multi-muscle synergies and early postural adjustments during step initiation.Experimental brain research · 2026Article
- Smartphone-Based Multimodal Digital Biomarker Integration for Parkinson's Disease Screening and Diagnostic Support.Neurology and therapy · 2026Article
- Functional changes in spinal circuitry in essential tremor revealed with analysis of intramuscle synergies.Journal of neurophysiology · 2026Article
- An Electromyographic Study Comparing Muscle Function During Supination and Pronation of the Forearm.Cureus · 2026Article
- Stability of performance in a hierarchical system during isometric force production and effects of visual feedback.Experimental brain research · 2025Article
- Sit-to-stand and stand-to-sit kinematics in older adults with and without functional disability: A principal component analysis.Australasian journal on ageing · 2025Article
- Impairment in the behavioral control of body sway, gaze shift, and mental workload in Parkinson's disease.Scientific reports · 2025Article
- Carpal tunnel release surgery restores force control but not force coordination in CTS patients.Scientific reports · 2025Article
- A Comprehensive Understanding of Postural Tone Biomechanics: Intrinsic Stiffness, Functional Stiffness, Antagonist Coactivation, and COP Dynamics in Post-Stroke Adults.Sensors (Basel, Switzerland) · 2025Article
- Article
- Arm-hand BOOST (AHA-BOOST) therapy to improve recovery of the upper limb after stroke: rationale and description by means of the TIDieR checklist.Frontiers in neurology · 2025Article
- Two aspects of feed-forward control of action stability: effects of action speed and unexpected events.Experimental brain research · 2024Article
- Infant vocal productions coincide with body movements.Developmental science · 2024Article
- Unintentional drifts in performance during one-hand and two-hand finger force production.Experimental brain research · 2023Article
- Humans prioritize walking efficiency or walking stability based on environmental risk.PloS one · 2023Article
- Synergic control in asymptomatic welders during multi-finger force exertion and load releasing while standing.Neurotoxicology · 2022Article
- The Number and Structure of Muscle Synergies Depend on the Number of Recorded Muscles: A Pilot Simulation Study with OpenSim.Sensors (Basel, Switzerland) · 2022Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
The concept of synergy provides a theoretical framework for movement stability resulting from the neural organization of multiple elements (digits, muscles, etc.) that all contribute to salient performance variables. Although stability of performance is obviously important for steady-state tasks leading to high synergy indices, a feed-forward drop in synergy indices is seen in preparation to a quick action (i.e., anticipatory synergy adjustments, ASAs). We review recent studies of multi-finger and multi-muscle synergies that show decreased indices of synergies and ASAs in patients with Parkinson's disease (PD) or multisystem atrophy. In PD, the impairments in synergies and ASAs are partially reversed by dopaminergic drugs, and changes in synergy indices are present even in PD patients at earliest diagnosis. Taken together, these results point at subcortical structures that are crucial for proper control of movement stability. It is timely to introduce the concept of impaired control of stability as an objective, quantifiable, and theory-based clinical descriptor of movement disorders that can increase our understanding of the neural control of movement with all of its implications for clinical practice.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.