ReviewJournal of neurovirology2016
The brain's Geppetto-microbes as puppeteers of neural function and behaviour?
Review in Journal of neurovirology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Alteration of the Microbiome is Associated with Changes in Mating and Locomotion in Callosobruchus maculatus.Microbial ecology · 2026Article
- Healthy gut microbiomes are host-controllable microbiomes.Frontiers in microbiology · 2024Article
- Bile acids, bioactive signalling molecules in interoceptive gut-to-brain communication.The Journal of physiology · 2022Article
- Nutrition, Microbiota and Role of Gut-Brain Axis in Subjects with Phenylketonuria (PKU): A Review.Nutrients · 2020Review
- Sources of epigenetic variation and their applications in natural populations.Evolutionary applications · 2020Article
- Glucagon-Like Peptide-1 Secreting L-Cells Coupled to Sensory Nerves Translate Microbial Signals to the Host Rat Nervous System.Frontiers in cellular neuroscience · 2020Article
- Old Friends, immunoregulation, and stress resilience.Pflugers Archiv : European journal of physiology · 2019Review
- Why does the microbiome affect behaviour?Nature reviews. Microbiology · 2018Review
- Economic Holobiont: Influence of Parasites, Microbiota and Chemosignals on Economic Behavior.Frontiers in behavioral neuroscience · 2018Article
- The Role of the Intestinal Microbiome in Chronic Psychosocial Stress-Induced Pathologies in Male Mice.Frontiers in behavioral neuroscience · 2018Article
- A psychology of the human brain-gut-microbiome axis.Social and personality psychology compass · 2017Article
- An RNA Virome Associated to the Golden Orb-Weaver SpiderFrontiers in microbiology · 2017Article
- Neuroimmune Cross Talk in the Gut. Neuroendocrine and neuroimmune pathways contribute to the pathophysiology of irritable bowel syndrome.American journal of physiology. Gastrointestinal and liver physiology · 2016Review
- Mind-altering microbes.Journal of neurovirology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Research on the microbiome and its interaction with various host organs, including the brain, is increasingly gaining momentum. With more evidence establishing a comprehensive microbiota-gut-brain axis, questions have been raised as to the extent to which microbes influence brain physiology and behaviour. In parallel, there is a growing literature showing active behavioural manipulation in favour of the microbe for certain parasites. However, it seems unclear where the hidden majority of microbes are localised on the parasitism-mutualism spectrum. A long evolutionary history intimately connects host and microbiota, which complicates this classification. In this conceptual minireview, we discuss current hypotheses on host-microbe interaction and argue that novel experimental approaches and theoretical concepts, such as the hologenome theory, are necessary to incorporate transgenerational epigenetic inheritance of the microbiome into evolutionary theories.
Indexed as
Identifiers
26047662What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.