Observational studyWorld journal of urology2016
Observations and outcomes of urethroplasty for bulbomembranous stenosis after radiation therapy for prostate cancer.
Observational study in World journal of urology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Post pubertal outcome after use of oral mucosa in urethral reconstruction for hypospadias in prepubertal boys: a systematic review.Pediatric surgery international · 2025Pooled it
- Delineating the Long-Term Incidence of Urethral Complications After Prostate Cancer Treatment: A Population-Based Analysis.The Journal of urology · 2026Article
- Substitution urethroplasty for posterior urethral stenosis.Translational andrology and urology · 2025Article
- Contemporary management of radiation-associated posterior urethral stenosis: a narrative review.Translational andrology and urology · 2025Review
- Optilume balloon dilation for radiation induced posterior urethral stenosis: a multi-institutional experience.BMC urology · 2025Article
- Long-term follow-up suggests high satisfaction rates for bulbomembranous radiation-induced urethral stenoses treated with anastomotic urethroplasty.World journal of urology · 2023Article
- Complications after Prostate Cancer Treatment: Pathophysiology and Repair of Post-Radiation Urethral Stricture Disease.Journal of clinical medicine · 2023Review
- Pelvic radiation-induced urinary strictures: etiology and management of a challenging disease.World journal of urology · 2023Review
- Devastated Bladder Outlet in Pelvic Cancer Survivors: Issues on Surgical Reconstruction and Quality of Life.Journal of clinical medicine · 2021Review
- Multi-Institutional Study of Dorsal Onlay Urethroplasty of the Membranous Urethra after Endoscopic Prostate Procedures: Operative Results, Continence, Erectile Function and Patient Reported Outcomes.Journal of clinical medicine · 2021Article
- A multi-institutional critical assessment of dorsal onlay urethroplasty for post-radiation urethral stenosis.World journal of urology · 2021Article
- Urological complications after radiation therapy-nothing ventured, nothing gained: a Narrative Review.Translational cancer research · 2021Review
- Current Management of Membranous Urethral Strictures Due to Radiation.Frontiers in surgery · 2021Review
- Long-term outcomes of anastomotic urethroplasty for radiation-induced strictures.World journal of urology · 2020Article
- Canadian Urological Association guideline on male urethral stricture.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2020Article
- Histologic characterization of the post-radiation urethral stenosis in men treated for prostate cancer.World journal of urology · 2020Article
- Posterior urethral stenosis after prostate cancer treatment: contemporary options for definitive management.Translational andrology and urology · 2018Review
- Article
- Reconstruction of Membranous Urethral Strictures.Current urology reports · 2018Review
- Management of Urethral Stricture and Bladder Neck Contracture Following Primary and Salvage Treatment of Prostate Cancer.Current urology reports · 2017Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeBulbomembranous stenosis is a significant complication of radiotherapy for prostate cancer. Our purpose is to report outcomes of urethroplasty for radiation-induced bulbomembranous urethral stenoses.
methodsThirty-five patients underwent urethroplasty for refractory radiation-induced bulbomembranous stenoses from January 2004 to November 2013. Patients had a minimum follow-up of 12 months with routine cystoscopy at 6 and 12 months. Primary outcome was urethral patency, and secondary outcomes were 90-day complications, de novo incontinence, de novo erectile dysfunction and bothersome LUTS. Outcomes were compared using Fisher's exact test.
resultsOf the 35 patients, 20 and 15 had stenosis related to external beam radiation therapy and brachytherapy, respectively. Mean stricture length was 3.5 cm. Reconstruction was performed using anastomotic urethroplasty in 23 patients (65.7 %), while 12 required tissue transfer as a buccal mucosa graft (20.0 %) or penile island flap (14.3 %). With 50.5 months of follow-up, thirty patients (85.7 %) achieved cystoscopic patency with no significant difference between techniques (p = 0.32). A 90-day complication rate of 31.4 % was observed (all Clavien 1-2) with no difference between techniques (p = 1.00). Adverse change in continence occurred in 25.7 % of patients (13.3 % in those without previous TURP). Postoperatively, persisting storage LUTS occurred in 40.0 and 30.4 % described adverse change in erectile function (exclusively in the anastomotic urethroplasty group).
conclusionsReconstruction of radiation-induced bulbomembranous stenosis yields satisfying patency rates. However, radiation-induced urethral stenosis is not an isolated problem as many patients suffer from storage symptoms, erectile dysfunction or incontinence as a consequence of treatment either before or after urethroplasty.
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