ReviewThe Journal of steroid biochemistry and molecular biology2015
The next 150 years of congenital adrenal hyperplasia.
Review in The Journal of steroid biochemistry and molecular biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Crinecerfont Lowers Elevated Hormone Markers in Adults With 21-Hydroxylase Deficiency Congenital Adrenal Hyperplasia.The Journal of clinical endocrinology and metabolism · 2022Trial
- Clinical burden of classic congenital adrenal hyperplasia and glucocorticoid-related complications: a claims analysis.Journal of the Endocrine Society · 2026Article
- Clinical and molecular characteristics of simple virilizing congenital adrenal hyperplasia due to 21-hydroxylase deficiency: insight from a tertiary pediatric center in Vietnam.Annals of pediatric endocrinology & metabolism · 2025Article
- Neonatal presentation of congenital adrenal hyperplasia accompanied by isolated cleft palate: case report.Oxford medical case reports · 2025Article
- Design, Synthesis, and Biological Evaluations of Novel Thiazolo[4,5-d]pyrimidine Corticotropin Releasing Factor (CRF) Receptor Antagonists as Potential Treatments for Stress Related Disorders and Congenital Adrenal Hyperplasia (CAH).Molecules (Basel, Switzerland) · 2024Article
- Crinecerfont, a CRF1 Receptor Antagonist, Lowers Adrenal Androgens in Adolescents With Congenital Adrenal Hyperplasia.The Journal of clinical endocrinology and metabolism · 2023Article
- Genotype-phenotype correlation in patients with 21-hydroxylase deficiency.Frontiers in endocrinology · 2023Article
- Treatment patterns and unmet needs in adults with classic congenital adrenal hyperplasia: A modified Delphi consensus study.Frontiers in endocrinology · 2022Article
- Disorders of the adrenal cortex: Genetic and molecular aspects.Frontiers in endocrinology · 2022Review
- Polycystic Ovary Syndrome Among Female Adolescents With Congenital Adrenal Hyperplasia.Cureus · 2021Article
- Non-Classical Congenital Adrenal Hyperplasia-Causing Alleles in Adolescent Girls with PCOS and in Risk Group for PCOS Development.Diagnostics (Basel, Switzerland) · 2021Article
- Morphologic and Molecular Characterization of Adrenals and Adrenal Rest Affected by Congenital Adrenal Hyperplasia.Frontiers in endocrinology · 2021Article
- Development of a putative adverse outcome pathway network for male rat reproductive tract abnormalities with specific considerations for the androgen sensitive window of development.Current research in toxicology · 2021Article
- Evaluation of a Two-Tier Screening Pathway for Congenital Adrenal Hyperplasia in the New South Wales Newborn Screening Programme.International journal of neonatal screening · 2020Article
- The human adrenal cortex: growth control and disorders.Clinics (Sao Paulo, Brazil) · 2018Review
- [17α-Hydroxylase deficiency with severe hypertension as the initial symptom in a child].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2018Article
- 46,XY Disorder of Sex Development Caused by 17Case reports in endocrinology · 2018Article
- A novel splice site variant in CYP11A1 in trans with the p.E314K variant in a male patient with congenital adrenal insufficiency.Molecular genetics & genomic medicine · 2017Article
- 17α‑hydroxylase/17,20‑lyase deficiency in congenital adrenal hyperplasia: A case report.Molecular medicine reports · 2017Article
- A Practical Forensic Approach to Fatal Pediatric Endocrinopathies.Academic forensic pathology · 2016Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Congenital adrenal hyperplasias (CAH) are a group of autosomal recessive defects in cortisol biosynthesis. Substantial progress has been made since the description of the first report, 150 years ago. This article reviews some of the recent advances in the genetics, diagnosis and treatment of CAH. In addition, we underline the aspects where further progress is required, including, among others, better diagnostic modalities for the mild phenotype and for some of the rare forms of disease, elucidation of epigenetic factors that lead to different phenotypes in patients with identical genotype and expending on treatment options for controlling the adrenal androgen excess.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.