Evidence map›Paper›PMID 2604709›Full record

ArticleThe Biochemical journal1989

Kallikrein-gene expression in the rat gastrointestinal tract.

P J Fuller, K Verity, B A Matheson, J A Clements

Open access · bronzeAbstract read
In one paragraph

Article in The Biochemical journal, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Development biology of the renal kallikrein-kinin system.Pediatric nephrology (Berlin, Germany) · 1994
    Review
  3. Molecular aspects of kallikrein and kininogen in the maturing kidney.Pediatric nephrology (Berlin, Germany) · 1993
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

P J FullerMedical Research Centre, Prince Henry's Hospital, Melbourne, Victoria, Australia.
K Verity
B A Matheson
J A Clements
Prince of Wales Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The serine proteinase glandular kallikrein has been demonstrated in the gastrointestinal tract, although there is some doubt as to whether it is synthesized there or derives from exocrine-gland secretions. Using a rat pancreatic kallikrein cRNA probe we have demonstrated kallikrein-like gene expression in the corpus, duodenum, jejunum, ileum, caecum and colon, and compared the pattern of expression with that of the gastrointestinal peptides somatostatin, gastrin and glucagon. In addition, using a panel of oligonucleotide probes specific for various members of the rat kallikrein-gene family, we have shown that the kallikrein-like gene expressed appears to be expressed as true kallikrein.

Indexed as

Digestive System Physiological PhenomenaAnimalsBlotting, NorthernGastrinsGene Expression Regulation, EnzymologicGlucagonKallikreinsOligonucleotide ProbesRatsRNA, MessengerRNA ProbesTissue DistributionTubulinGastrinsGlucagonKallikreinsOligonucleotide ProbesRNA, MessengerRNA ProbesTubulin

Identifiers

PMID2604709
PMCPMC1133556
OpenAlexW151755804

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.