Trial reportOncotarget2015
Effects of eight weeks of aerobic interval training and of isoinertial resistance training on risk factors of cardiometabolic diseases and exercise capacity in healthy elderly subjects.
Trial report in Oncotarget, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04840368 (Cardiovascular Risk and Functional Responses From Dancing at Home Compared With Walking in Elderly Individuals With and Without Type 2 Diabetes Mellitus), which is not on this map. Cited by 34 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cardiovascular Risk and Functional Responses From Dancing at Home Compared With Walking in Elderly Individuals With and Without Type 2 Diabetes Mellitus: A Randomized Controlled Trial.
Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- Muscle Protein Synthesis Responses Following Aerobic-Based Exercise or High-Intensity Interval Training with or Without Protein Ingestion: A Systematic Review.Sports medicine (Auckland, N.Z.) · 2022Pooled it
- The Effects of High-Intensity Interval Training (HIIT) on Fall Risk Factors in Healthy Older Adults: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Equipment-free, unsupervised high intensity interval training elicits significant improvements in the physiological resilience of older adults.BMC geriatrics · 2022Trial
- Feasibility and effects of high-intensity interval training in older adults living with HIV.Journal of sports sciences · 2021Trial
- High Intensity Interval Training Does Not Have Compensatory Effects on Physical Activity Levels in Older Adults.International journal of environmental research and public health · 2020Trial
- High-Intensity Interval Circuit Training Versus Moderate-Intensity Continuous Training on Functional Ability and Body Mass Index in Middle-Aged and Older Women: A Randomized Controlled Trial.International journal of environmental research and public health · 2019Trial
- Changes in pro-inflammatory markers and leucine concentrations in response to Nordic Walking training combined with vitamin D supplementation in elderly women.Biogerontology · 2017Trial
- Effects of different durations of high-intensity interval training or continuous training with/without metformin on lipid profile and malondialdehyde level in a rat model of polycystic ovary syndrome.Veterinary research forum : an international quarterly journal · 2026Article
- Effect of high-intensity interval training and resistance training on the follistatin and myostatin levels in gastrocnemius muscle of aged female rats.Biogerontology · 2025Article
- Article
- Individual cardiorespiratory fitness exercise prescription for older adults based on a back-propagation neural network.Frontiers in public health · 2025Article
- High intensity interval training vs. moderate intensity continuous training on aerobic capacity and functional capacity in patients with heart failure: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2024Review
- Effects of High-Intensity Functional Training (HIFT) on the Functional Capacity, Frailty, and Physical Condition of Older Adults with Mild Cognitive Impairment: A Blind Randomized Controlled Clinical Trial.Life (Basel, Switzerland) · 2023Article
- Easy Prediction of the Maximal Lactate Steady-State in Young and Older Men and Women.Journal of sports science & medicine · 2023Article
- Type 2 Diabetes Related Mitochondrial Defects in Peripheral Mononucleated Blood Cells from Overweight Postmenopausal Women.Biomedicines · 2023Article
- Improving Health Outcomes in Coronary Artery Disease Patients with Short-Term Protocols of High-Intensity Interval Training and Moderate-Intensity Continuous Training: A Community-Based Randomized Controlled Trial.Cardiovascular therapeutics · 2023Article
- Article
- Exercise engagement drives changes in cognition and cardiorespiratory fitness after 8 weeks of aerobic training in sedentary aging adults at risk of cognitive decline.Frontiers in rehabilitation sciences · 2022Article
- Effects of different exercise interventions on heart rate variability and cardiovascular health factors in older adults: a systematic review.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2021Review
- High-Intensity Interval Training in Older Adults: a Scoping Review.Sports medicine - open · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated the effect of 8 weeks of high intensity interval training (HIT) and isoinertial resistance training (IRT) on cardiovascular fitness, muscle mass-strength and risk factors of metabolic syndrome in 12 healthy older adults (68 yy ± 4). HIT consisted in 7 two-minute repetitions at 80%-90% of VËO2max, 3 times/w. After 4 months of recovery, subjects were treated with IRT, which included 4 sets of 7 maximal, bilateral knee extensions/flexions 3 times/w on a leg-press flywheel ergometer. HIT elicited significant: i) modifications of selected anthropometrical features; ii) improvements of cardiovascular fitness and; iii) decrease of systolic pressure. HIT and IRT induced hypertrophy of the quadriceps muscle, which, however, was paralleled by significant increases in strength only after IRT. Neither HIT nor IRT induced relevant changes in blood lipid profile, with the exception of a decrease of LDL and CHO after IRT. Physiological parameters related with aerobic fitness and selected body composition values predicting cardiovascular risk remained stable during detraining and, after IRT, they were complemented by substantial increase of muscle strength, leading to further improvements of quality of life of the subjects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.