ArticleScientific reports2015
DNA double-strand breaks alter the spatial arrangement of homologous loci in plant cells.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Chromatin dynamics and RNA metabolism are double-edged swords for the maintenance of plant genome integrity.Nature plants · 2024Review
- Article
- The plant-specific DDR factor SOG1 increases chromatin mobility in response to DNA damage.EMBO reports · 2022Article
- DMC1 attenuates RAD51-mediated recombination in Arabidopsis.PLoS genetics · 2022Article
- RAD54 is essential for RAD51-mediated repair of meiotic DSB in Arabidopsis.PLoS genetics · 2021Article
- Application and prospects of CRISPR/Cas9-based methods to trace defined genomic sequences in living and fixed plant cells.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2020Review
- LSD1-LIKE1-Mediated H3K4me2 Demethylation Is Required for Homologous Recombination Repair.Plant physiology · 2019Article
- Characterization of DNA Repair Foci in Root Cells ofFrontiers in plant science · 2019Article
- Proteasomal degradation of BRAHMA promotes Boron tolerance in Arabidopsis.Nature communications · 2018Article
- Auxin decreases chromatin accessibility through the TIR1/AFBs auxin signaling pathway in proliferative cells.Scientific reports · 2018Article
- Pyruvate kinase M2 phosphorylates H2AX and promotes genomic instability in human tumor cells.Oncotarget · 2017Article
- Visualization of specific repetitive genomic sequences with fluorescent TALEs in Arabidopsis thaliana.Journal of experimental botany · 2016Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chromatin dynamics and arrangement are involved in many biological processes in nuclei of eukaryotes including plants. Plants have to respond rapidly to various environmental stimuli to achieve growth and development because they cannot move. It is assumed that the alteration of chromatin dynamics and arrangement support the response to these stimuli; however, there is little information in plants. In this study, we investigated the chromatin dynamics and arrangement with DNA damage in Arabidopsis thaliana by live-cell imaging with the lacO/LacI-EGFP system and simulation analysis. It was revealed that homologous loci kept a constant distance in nuclei of A. thaliana roots in general growth. We also found that DNA double-strand breaks (DSBs) induce the approach of the homologous loci with γ-irradiation. Furthermore, AtRAD54, which performs an important role in the homologous recombination repair pathway, was involved in the pairing of homologous loci with γ-irradiation. These results suggest that homologous loci approach each other to repair DSBs, and AtRAD54 mediates these phenomena.
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