Evidence map›Paper›PMID 26046012›Full record

ArticleCurrent sleep medicine reports2015

Sleep in Autism Spectrum Disorders.

Olivia J Veatch, Angela C Maxwell-Horn, Beth A Malow

Open access · bronzeAbstract read
In one paragraph

Article in Current sleep medicine reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 3 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 3 syntheses or guidelines pooled it, 107 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Trial
  5. Trial
  6. Review
  7. Review
  8. Article
  9. Sleep and activity patterns in autism.Autism : the international journal of research and practice · 2026
    Article
  10. Circadian preference and quality of life in adults with autism spectrum disorder: a Brazilian cross-sectional self-reported survey.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Comparative Analysis of Autistic Women Across the Lifespan: Childhood vs. Adulthood Diagnosis.Autism research : official journal of the International Society for Autism Research · 2025
    Article
  19. Review
  20. Association ofJournal of clinical medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Olivia J VeatchSleep Disorders Division, Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA.
Angela C Maxwell-HornDepartment of Developmental Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Beth A MalowSleep Disorders Division, Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA.
Vanderbilt University Medical Center · US

Funding

TRAINING PROGRAM/RESPIRATORY NEUROBIOLOGY AND SLEEPT32HL007713 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI PACK, ALLAN I · 1992 to 2022
$11.9M
Research Project: Sensory and Multisensory Contributions to AutismU54HD083211 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DYKENS, ELISABETH MAY · 2015 to 2019
$7.1M
Melatonin for Sleep in Children with Autism: Safety, Tolerability, and DosingR01HD059253 · NICHD · VANDERBILT UNIVERSITY · PI MALOW, BETH A · 2008 to 2009
$873k
NHLBI NIH HHS T32 HL007713NICHD NIH HHS R01 HD059253NICHD NIH HHS U54 HD083211
6 · The paper itself

Abstract

Autism spectrum disorders (ASD) are common neurodevelopmental conditions, affecting 1 in 68 children. Sleep disturbance, particularly insomnia, is very common in children diagnosed with ASD, with evidence supporting overlapping neurobiological and genetic underpinnings. Disturbed sleep exacerbates core and related ASD symptoms and has a substantial negative impact on the entire family. Treatment of sleep disturbance holds promise for ameliorating many of the challenging behavioral symptoms that children with ASD and their families face. Behavioral and pharmacological studies indicate promising approaches to treating sleep disturbances in this population. Awareness of treatment options is particularly important as parents and clinicians may believe that sleep disturbance is part of autism and refractory to therapy. In addition, autism symptoms refractory to treatment with conventional psychiatric medications may improve when sleep is addressed. Additional evidence-based studies are needed, including those that address the underlying biology of this condition.

Indexed as

AutismBehavioral TherapyBiochemistryDiagnosisGeneticsNeurodevelopmental DisordersPediatric Sleep DisordersPharmacotherapy

Identifiers

PMID26046012
PMCPMC4450800
OpenAlexW2073184661

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.