Evidence map›Paper›PMID 26045973›Full record

ArticleJournal of molecular biomarkers & diagnosis2014

Identification of a Peptide from

Benjamin M Larimer, Susan L Deutscher

Open access · bronzeAbstract read
In one paragraph

Article in Journal of molecular biomarkers & diagnosis, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Progress of EGFL6 in angiogenesis and tumor development.International journal of clinical and experimental pathology · 2022
    Review
  3. The emerging role of EGFL6 in angiogenesis and tumor progression.International journal of medical sciences · 2020
    Review
  4. Article
  5. Article
  6. Article
  7. High EGFL6 expression is associated with clinicopathological characteristics in colorectal cancer.International journal of clinical and experimental pathology · 2018
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Benjamin M LarimerResearch Service, Harry S. Truman Veterans Memorial Hospital, Columbia, MO, USA ; Department of Biochemistry, University of Missouri, Columbia, MO, USA.
Susan L DeutscherResearch Service, Harry S. Truman Veterans Memorial Hospital, Columbia, MO, USA ; Department of Biochemistry, University of Missouri, Columbia, MO, USA.
Memorial Hospital · US

Funding

Multivalent Nanophage Engineered as Dual Receptor Cancer Theranostic Agents.R21CA179069 · NCI · UNIVERSITY OF MISSOURI-COLUMBIA · PI DEUTSCHER, SUSAN L · 2013 to 2014
$358k
Phage Display for Improved Peptide-Based Tumor Targeting and Imaging AgentsI01BX000964 · VA · HARRY S. TRUMAN MEMORIAL VA HOSPITAL · PI DEUTSCHER, SUSAN L, SMITH, CHARLES J · 2011 to 2025
–
BLRD VA I01 BX000964NCI NIH HHS R21 CA179069
6 · The paper itself

Abstract

backgroundA crucial step in tumorigenesis is the recruitment of novel vasculature to the site of neoplasia. Currently, a number of high throughput techniques are employed to identify genes, mRNA and proteins that are aberrantly expressed in tumor vasculature. One drawback of such techniques is the lack of functional

objectivesIt was hypothesized that an

methodsFollowing four rounds of

resultsEgfl6 mRNA expression was demonstrated in MDA-MB-435 cells and EGFL6 protein was secreted from these cells. Based on homology of 3-G03 to EGFL6, an EGFL6 peptide was synthesized and shown to target MDA-MB-435 cells. EGFL6 peptide was radiolabeled with

Indexed as

Breast cancerEGFL6Molecular imagingPeptidesPhage displaySPECT/CTTumor vasculature

Identifiers

PMID26045973
PMCPMC4451856
OpenAlexW2155386597

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.