Evidence map›Paper›PMID 26045700›Full record

ArticleHepatitis monthly2015

Duct-to-Duct Biliary Anastomosis Yields Similar Outcomes to Roux-en-Y Hepaticojejunostomy in Liver Transplantation for Primary Sclerosing Cholangitis.

Bandar Al-Judaibi, Roberto Hernandez Alejandro, Julia Uhanova, Paul Marotta, Mahmoud Mosli, Natasha Chandok

Open access · hybridAbstract read
In one paragraph

Article in Hepatitis monthly, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Bandar Al-JudaibiMulti Organ Transplant Unit, Departments of Medicine and General Surgery, University of Western Ontario, London, Canada ; Department of Medicine, King Saud University, Riyadh, Saudi Arabia.
Roberto Hernandez AlejandroMulti Organ Transplant Unit, Departments of Medicine and General Surgery, University of Western Ontario, London, Canada.
Julia UhanovaMulti Organ Transplant Unit, Departments of Medicine and General Surgery, University of Western Ontario, London, Canada.
Paul MarottaMulti Organ Transplant Unit, Departments of Medicine and General Surgery, University of Western Ontario, London, Canada.
Mahmoud MosliDepartment of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Natasha ChandokMulti Organ Transplant Unit, Departments of Medicine and General Surgery, University of Western Ontario, London, Canada.
Western University · CAKing Abdulaziz University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile Roux-en-Y hepaticojejunostomy (RYH) is the common anastomotic technique for liver transplantation (LT) in patients with primary sclerosing cholangitis (PSC), duct-to-duct (DD) reconstruction may be used if the recipient common bile duct is normal. There are conflicting observational data on the rate of success of DD reconstruction versus RYH, in PSC.

objectivesThe aim of this study was to assess the safety and efficacy of DD anastomosis, compared to RYH reconstruction, among adults transplanted for PSC. PATIENTS AND

methodsAll adult patients, who underwent primary LT for PSC between 1990 and 2012, were evaluated, according to type of biliary reconstruction. Recipient and graft survival, postoperative medical and surgical complications, and postoperative resource utilization rates were compared between the two groups.

resultsTotally, 73 patients fulfilled the inclusion criteria. Of them, 58 had RYH and 15 had DD reconstruction. A total of 53 subjects (73%) were male, with the mean age ± standard deviation at LT of 43.3 ± 14.4 years. Rates of recipient mortality, graft failure, biliary complications, acute cellular rejection, and reoperation were similar in both groups. Postoperative cholangiography was used more frequently in patients with DD reconstruction (33.3% vs. 8.6%, P = 0.026).

conclusionsIn selected recipients with PSC, DD reconstruction is a safe and efficacious technique, with long-term clinical outcomes comparable to RYH.

Indexed as

Liver TransplantationPrimary Sclerosing CholangitisRoux-en-Y Anastomosis

Identifiers

PMID26045700
PMCPMC4451269
OpenAlexW262612851

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.