ArticlePopulation health metrics2015
Should additional domains be added to the EQ-5D health-related quality of life instrument for community-based studies? An analytical descriptive study.
Article in Population health metrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Psychometric properties of the health-related quality of life instrument with 8 items: a systematic review and meta-analysis.Health and quality of life outcomes · 2026Pooled it
- Psychometric properties of the EQ-5D-5L: a systematic review of the literature.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Pooled it
- Effects of beta-blockers on quality of life and well-being in patients with myocardial infarction and preserved left ventricular function-a prespecified substudy from REDUCE-AMI.European heart journal. Cardiovascular pharmacotherapy · 2025Trial
- Identifying and developing EQ-5D-5L bolt-on items for Chinese chronic obstructive pulmonary disease patients.Health and quality of life outcomes · 2025Article
- Developing and testing a patient-reported outcome measure for patients with sleep disturbances using EQ-5D and condition-specific bolt-ons: a mixed method study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Quality of life and financial implications of depression in India.Indian journal of psychiatry · 2025Article
- Exploring potential EQ-5D bolt-on dimensions with a qualitative approach: an interview study in Hong Kong SAR, China.Health and quality of life outcomes · 2024Article
- Enhancing EQ-5D-5L Sensitivity in Capturing the Most Common Symptoms in Post-COVID-19 Patients: An Exploratory Cross-Sectional Study with a Focus on Fatigue, Memory/Concentration Problems and Dyspnea Dimensions.International journal of environmental research and public health · 2024Article
- Article
- Extending the EQ-5D: the case for a complementary set of 4 psycho-social dimensions.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Sensitivity of the EQ-5D-5L for fatigue and cognitive problems and their added value in Q-fever patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- Assessing Health-Related Quality of Life of Adult Patients with Intermediate Burns: The Added Value of an Itching and Cognition Item for the EQ-5D: A Retrospective Observational Study.European burn journal · 2022Article
- The relation between EQ-5D and fatigue in a Dutch general population sample: an explorative study.Health and quality of life outcomes · 2021Article
- Article
- Does the EQ-5D-5L benefit from extension with a cognitive domain: Testing a multi-criteria psychometric strategy in trauma patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020Article
- Health-related quality of life in injury patients: the added value of extending the EQ-5D-3L with a cognitive dimension.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019Article
- The added value of the EQ-5D with a cognition dimension in injury patients with and without traumatic brain injury.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019Article
- Relative importance of the EQ-5D five dimensions among patients with chronic diseases in South Korea - a comparison with the general population preference weights.Health and quality of life outcomes · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is increasing interest in monitoring the health-related quality of life (HRQoL) of populations as opposed to clinical populations. The EQ-5D identifies five domains as being most able to capture the HRQoL construct. The question arises as to whether these domains are adequate within a community-based population or whether additional domains would add to the explanatory power of the instrument.
methodsAs part of a community-based survey, the responses of 310 informants who reported at least one problem in one domain filled in the EQ-5D three-level version and the WHOQOL-BREF (World Health Organization Quality of Life Scale - Abbreviated version). Using the EQ-5D visual analogue scale (VAS) of rating of health as a dependent variable, the five EQ-5D and four selected WHOQOL-BREF items were entered as dummy variables in multiple regression analysis.
resultsThe additional domains increased the explanatory power of the model from 52 % (EQ-5D only) to 57 % (all domains). The coefficients of Self-Care and Usual Activities were not significant in any model. The most parsimonious model included the EQ-5D domains of Mobility, Pain/Discomfort, Anxiety/Depression, Concentration, and Sleep (adjusted r(2) = .57).
conclusionsThe EQ-5D-3L performed well, but the addition of domains such as Concentration and Sleep increased the explanatory power. The user needs to weigh the advantage of using the EQ-5D, which allows for the calculation of a single summary index, against the use of a set of domains that are likely to be more responsive to differences in HRQoL within community living respondents. The poor predictive power of the Self-Care and Usual Activities domains within this context needs to be further examined.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.