Evidence map›Paper›PMID 26045648›Full record

ArticleP & T : a peer-reviewed journal for formulary management2015

Pharmacological therapies for autism spectrum disorder: a review.

Sheena LeClerc, Deidra Easley

Registry-linked trialAbstract read
PubMed Full text at PMC
In one paragraph

Article in P & T : a peer-reviewed journal for formulary management, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03887754 (Therapeutic Issues for Autism Spectrum Disorders), which is not on this map. Cited by 67 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03887754 phase2completednot on this mapstarted 2016, after this paper: background citation

Therapeutic Issues for Autism Spectrum Disorders: a Clinical Trial

TypeinterventionalSponsorMinia UniversityRan2016 to 2018Enrolled80ConditionsAutism Spectrum DisorderArmsRisperidone, hyperbaric oxygen therapy, Non specific Multivitamin
3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  15. Potentiation of Nigra-Striatal Dopaminergic Projection Underpins Core Autism-Like Behaviors in Valproate-Exposed Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sheena LeClerc
Deidra Easley

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medications are often added to behavioral therapy to help patients with autism spectrum disorder function successfully. This review discusses approved and off-label pharmacotherapeutic options for the various symptoms of the disorder.

Identifiers

PMID26045648
PMCPMC4450669

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.