Evidence map›Paper›PMID 26045577›Full record

ReviewAJNR. American journal of neuroradiology2015

Hot Topics in Research: Preventive Neuroradiology in Brain Aging and Cognitive Decline.

C A Raji, H Eyre, S H Wei, D E Bredesen, S Moylan, M Law, G Small, P M Thompson, R M Friedlander, D H Silverman and 5 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in AJNR. American journal of neuroradiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. The Brain Economy: Advancing Brain Science to Better Understand the Modern Economy.The Malaysian journal of medical sciences : MJMS · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Convergence Science Arrives: How Does It Relate to Psychiatry?Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry · 2017
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

C A RajiFrom the Departments of Radiology (C.A.R., S.H.W., T.A.H., N.S.) cyrusraji@gmail.com.
H EyrePsychiatry (H.E., G.S.) Discipline of Psychiatry (H.E., B.T.B.), University of Adelaide, Adelaide, South Australia, Australia.
S H WeiFrom the Departments of Radiology (C.A.R., S.H.W., T.A.H., N.S.).
D E BredesenNeurology (D.E.B.).
S MoylanSchool of Medicine (S.M.), Deakin University, Geelong, Victoria, Australia.
M LawDepartment of Radiology (M.L.).
G SmallPsychiatry (H.E., G.S.).
P M ThompsonLaboratory of Neuroimaging (P.M.T., A.W.T.), University of Southern California, Los Angeles, California.
R M FriedlanderDepartment of Neurosurgery (R.M.F.), University of Pittsburgh, Pittsburgh, Pennsylvania.
D H SilvermanNuclear Medicine (D.H.S.), University of California at Los Angeles Medical Center, University of California at Los Angeles, Los Angeles, California.
B T BauneDiscipline of Psychiatry (H.E., B.T.B.), University of Adelaide, Adelaide, South Australia, Australia.
T A HoangFrom the Departments of Radiology (C.A.R., S.H.W., T.A.H., N.S.).
N SalamonFrom the Departments of Radiology (C.A.R., S.H.W., T.A.H., N.S.).
A W TogaLaboratory of Neuroimaging (P.M.T., A.W.T.), University of Southern California, Los Angeles, California.
M W VernooijDepartments of Radiology and Epidemiology (M.W.V.), Erasmus University Medical Center, Rotterdam, the Netherlands.

Funding

Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
VASCULAR RISK AND COGNITIVE STATUS IN A LATINO POPULATIONP50AG005142 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ARANDA, MARIA P. · 1985 to 2019
$41.0M
TR&D3: Intrinsic Surface MappingP41EB015922 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI VAN HORN, JOHN DARRELL · 2012 to 2022
$14.1M
Growth factors, neuroinflammation, exercise, and brain integrityRF1AG041915 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI THOMPSON, PAUL M · 2014 to 2014
$2.9M
NIA NIH HHS P50 AG005142NIA NIH HHS RF1 AG041915NIA NIH HHS U01 AG024904NIA NIH HHS U01AG024904NIBIB NIH HHS P41 EB015922NIBIB NIH HHS P41EB015922
6 · The paper itself

Abstract

Preventive neuroradiology is a new concept supported by growing literature. The main rationale of preventive neuroradiology is the application of multimodal brain imaging toward early and subclinical detection of brain disease and subsequent preventive actions through identification of modifiable risk factors. An insightful example of this is in the area of age-related cognitive decline, mild cognitive impairment, and dementia with potentially modifiable risk factors such as obesity, diet, sleep, hypertension, diabetes, depression, supplementation, smoking, and physical activity. In studying this link between lifestyle and cognitive decline, brain imaging markers may be instrumental as quantitative measures or even indicators of early disease. The purpose of this article is to provide an overview of the major studies reflecting how lifestyle factors affect the brain and cognition aging. In this hot topics review, we will specifically focus on obesity and physical activity.

Indexed as

Diagnostic ImagingAgedAge FactorsAgingAlzheimer DiseaseBrainCognitive DysfunctionDepressionDiabetes ComplicationsHumansHypertensionLife StyleResearchRisk Factors

Identifiers

PMID26045577
PMCPMC4600413

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.