Evidence map›Paper›PMID 26045467›Full record

ArticleSexually transmitted infections2015

Factors associated with uptake of services to prevent mother-to-child transmission of HIV in a community cohort in rural Tanzania.

Annabelle Gourlay, Alison Wringe, Jim Todd, Caoimhe Cawley, Denna Michael, Richard Machemba, Georges Reniers, Mark Urassa, Basia Zaba

Open access · hybridAbstract read
In one paragraph

Article in Sexually transmitted infections, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Annabelle GourlayFaculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.
Alison WringeFaculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.
Jim ToddFaculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.
Caoimhe CawleyFaculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.
Denna MichaelNational Institute for Medical Research, Mwanza, Tanzania.
Richard MachembaNational Institute for Medical Research, Mwanza, Tanzania.
Georges ReniersFaculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.
Mark UrassaNational Institute for Medical Research, Mwanza, Tanzania.
Basia ZabaFaculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.
London School of Hygiene & Tropical Medicine · GBNational Institute for Medical Research · TZ

Funding

East Africa International Epidemiology Database to evaluate AIDS (IeDEA) Regional ConsortiumU01AI069911 · NIAID · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI AGGREY SEMWENDERO SEMEERE, Kara Kay Wools-Kaloustian · 2006 to 2026
$57.7M
Medical Research Council EPCPAC79Medical Research Council G0902143NIAID NIH HHS 3U01AI069911NIAID NIH HHS U01 AI069911
6 · The paper itself

Abstract

objectivesThis study aimed to identify factors associated with access to HIV care and antiretroviral (ARV) drugs for prevention of mother-to-child transmission (PMTCT) of HIV among HIV-positive pregnant women in a community cohort in rural Tanzania (Kisesa).

methodsKisesa-resident women who tested HIV-positive during HIV serosurveillance and were pregnant (while HIV-positive) between 2005 and 2012 were eligible. Community cohort records were linked to PMTCT and HIV clinic data from four facilities (PMTCT programme implemented in 2009; referrals to city-based hospitals since 2005) to ascertain service use. Factors associated with access to HIV care and ARVs during pregnancy were analysed using logistic regression.

resultsOverall, 24% of women accessed HIV care and 12% accessed ARVs during pregnancy (n=756 pregnancies to 420 women); these proportions increased over time. In multivariate analyses for 2005-2012, being married, prior voluntary counselling and testing, increasing age, increasing year of pregnancy and increasing duration of infection were independently associated with access to care and ARVs. Residence in roadside areas was an independent predictor of access to care but not ARVs. There was no evidence of an interaction with time period.

conclusionsAccess to PMTCT services was low in this rural setting but improved markedly over time. There were fairly few sociodemographic differentials although support for young women and those without partners may be needed. Further decentralisation of HIV services to more remote areas, promotion of voluntary counselling and testing and implementation of Option B+ are likely to improve uptake and may bring women into care and treatment sooner after infection.

Indexed as

Health Services AccessibilityAdolescentAdultAnti-Retroviral AgentsCohort StudiesFemaleHIV InfectionsHumansInfantInfant, NewbornInfectious Disease Transmission, VerticalMalePregnancyRural PopulationTanzaniaYoung AdultAnti-Retroviral AgentsAFRICAANTIRETROVIRAL THERAPYHIVPREGNANCY

Identifiers

PMID26045467
PMCPMC4680170
OpenAlexW1823079874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.