Medicine. Progeria accelerates adult stem cell aging.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

10 citing papers in PubMed.

1. Deconstructing heterogeneity of replicative senescence in human mesenchymal stem cells at single cell resolution.GeroScience · 2024
   Article
2. Functional genomics, genetic risk profiling and cell phenotypes in neurodegenerative disease.Neurobiology of disease · 2020
   Review
3. The ageing epigenome and its rejuvenation.Nature reviews. Molecular cell biology · 2020
   Review
4. Nuclear Organization in Stress and Aging.Cells · 2019
   Review
5. Hutchinson-Gilford Progeria Syndrome-Current Status and Prospects for Gene Therapy Treatment.Cells · 2019
   Review
6. Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome.Protein & cell · 2018
   Article
7. High glucose induces the aging of mesenchymal stem cells via Akt/mTOR signaling.Molecular medicine reports · 2017
   Article
8. Evolution of Microbial Quorum Sensing to Human Global Quorum Sensing: An Insight into How Gap Junctional Intercellular Communication Might Be Linked to the Global Metabolic Disease Crisis.Biology · 2016
   Article
9. The Antiaging Gene Klotho Regulates Proliferation and Differentiation of Adipose-Derived Stem Cells.Stem cells (Dayton, Ohio) · 2016
   Article
10. Molecular insights into the premature aging disease progeria.Histochemistry and cell biology · 2016
    Review

Corrections and comments

• Comment on
  Aging stem cells. A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging.2015

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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