SynthesisMuscle & nerve2015
Quantitative neuromuscular ultrasound in intensive care unit-acquired weakness: A systematic review.
Synthesis in Muscle & nerve, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 75 citations in OpenAlex.
- Early prediction of intensive care unit-acquired weakness using quadriceps ultrasound and routine clinical variables: development and temporal validation of a prospective multicentre machine-learning model.Journal of intensive care · 2026Article
- Differences in muscle atrophy between the lower limbs and the accessory respiratory muscles in critically ill patients.Journal of medical ultrasonics (2001) · 2025Article
- Potential diagnostic tools for intensive care unit acquired weakness: A systematic review.International journal of nursing studies advances · 2025Review
- Predicting early diagnosis of intensive care unit-acquired weakness in septic patients using critical ultrasound and biological markers.BMC anesthesiology · 2025Observational
- Impact of High-Protein Enteral Feeding on Skeletal Muscle Mass Changes in Critically Ill Patients: A Randomized Controlled Trial.Medical journal of the Islamic Republic of Iran · 2025Article
- Opportunistic screening for long-term muscle wasting in critically ill patients: insights from an acute pancreatitis cohort.European journal of medical research · 2024Article
- Association of tissue oxygen saturation levels with skeletal muscle injury in the critically ill.Scientific reports · 2024Article
- Neuromuscular disorders in women and men with spinal cord injury are associated with changes in muscle and tendon architecture.The journal of spinal cord medicine · 2023Article
- The Loss of Temporal Muscle Volume is Associated with Poor Outcome in Patients with Subarachnoid Hemorrhage: An Observational Cohort Study.Neurocritical care · 2023Observational
- Intermittent body composition analysis as monitoring tool for muscle wasting in critically ill COVID-19 patients.Annals of intensive care · 2023Article
- Postoperative muscle loss, protein intake, physical activity and outcome associations.The British journal of surgery · 2023Observational
- Feasibility of Muscle Endurance Testing in Critically Ill Trauma Patients: A Pilot Study.Healthcare (Basel, Switzerland) · 2022Article
- The time course of disuse muscle atrophy of the lower limb in health and disease.Journal of cachexia, sarcopenia and muscle · 2022Review
- Investigating the rate of skeletal muscle atrophy in men and women in the intensive care unit: a prospective observational study.Scientific reports · 2022Observational
- Sonographic Evaluation of Muscle Echogenicity for the Detection of Intensive Care Unit-Acquired Weakness: A Pilot Single-Center Prospective Cohort Study.Diagnostics (Basel, Switzerland) · 2022Article
- Observational
- Changes in muscle ultrasound for the diagnosis of intensive care unit acquired weakness in critically ill patients.Scientific reports · 2021Article
- Sonographic muscle mass assessment in patients after cardiac surgery.World journal of cardiology · 2020Article
- Real-time shear wave ultrasound elastography: a new tool for the evaluation of diaphragm and limb muscle stiffness in critically ill patients.Critical care (London, England) · 2020Observational
- Clinical review: peripheral muscular ultrasound in the ICU.Annals of intensive care · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Intensive care unit-acquired weakness (ICU-AW) causes significant morbidity and impairment in critically ill patients. Recent advances in neuromuscular ultrasound (NMUS) allow evaluation of neuromuscular pathology early in critical illness. Here we review application of ultrasound in ICU-AW. MEDLINE-indexed articles were searched for terms relevant to ultrasound and critical illness. Two reviewers evaluated the resulting abstracts (n = 218) and completed full-text review (n = 13). Twelve studies and 1 case report were included. Ten studies evaluated muscle thickness or cross-sectional area (CSA): 8 reported a decrease, and 2 reported no change. Two studies reported preservation of muscle thickness in response to neuromuscular electrical stimulation, and 1 found no preservation. One study found decreases in gray-scale standard deviation, but no change in echogenicity. One study described increases in echogenicity and fasciculations. Ultrasound reliability in ICU-AW is not fully established. Further investigation is needed to identify ultrasound measures that reliably predict clinical, electrodiagnostic, and pathologic findings of ICU-AW.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.