ArticleBMJ open2015
Association between body mass index and onset of hypertension in men and women with and without diabetes: a cross-sectional study using national health data from the State of Kuwait in the Arabian Peninsula.
Article in BMJ open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 30 citations in OpenAlex.
- Urinary extracellular vesicle miRNA signature reflects pancreatic islet stress in type 2 diabetes.Journal of diabetes investigation · 2026Article
- Sex differences in the relationship between body mass index in Chinese adolescents and future risk of hypertension: a decade-long cohort study.BMC pediatrics · 2025Article
- Association between anthropometric indices and 5-year hypertension incidence in the general Japanese population.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Positive correlation between body weight and body mass index with blood pressure in young adults.Narra J · 2024Article
- BMI mediates the association of family medical history with self-reported hypertension and diabetes among older adults: Evidence from baseline wave of the longitudinal aging study in India.SSM - population health · 2022Article
- Hypertension in the Middle East: current state, human factors, and barriers to control.Journal of human hypertension · 2022Review
- Assessment of visceral adiposity index and lipid accumulation product index as markers of chronic kidney disease among diabetic and hypertensive patients at the Bamenda Regional Hospital, Cameroon: a cross-sectional study.The Pan African medical journal · 2022Article
- Trajectories of mid-life to elderly adulthood BMI and incident hypertension: the China Health and Nutrition Survey.BMJ open · 2021Article
- Obesity and cardiovascular disease in women.International journal of obesity (2005) · 2020Review
- Article
- Body fat change and 8-year incidence of hypertension: Korean Genome and Epidemiology Study.Journal of clinical hypertension (Greenwich, Conn.) · 2019Article
- Anthropometric Measures as Predictive Indicators of Metabolic Risk in a Population of "Holy WeekInternational journal of environmental research and public health · 2019Article
- Impact of Attending the Diwaniyyah on Kuwaiti Men's Health.American journal of men's health · 2018Article
- Primary prevention of cardiovascular disease in older adults in China.World journal of clinical cases · 2017Review
- Effect Modification by Age and Gender in the Correlation Between Diabetes Mellitus, Hypertension, and Obesity.Journal of primary care & community healthArticle
- Prevalence of poor glycemic and blood pressure control and pattern of drug use among primary health-care outpatients in Al Ahsa Saudi Arabia.International journal of health sciencesArticle
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4 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveObesity contributes directly to the risk of diabetes and hypertension. Effective management of diabetes is essential to prevent or delay the onset of comorbid hypertension. In this study, we delineate the association body mass index (BMI) has with risk and age at onset of hypertension and explore how this association is modulated by sex and the pre-existing condition of diabetes.
designCross-sectional study using retrospective data.
settingKuwait Health Network that integrates primary health and hospital laboratory data into a single system.
participantsWe considered 3904 native Kuwaiti comorbid individuals who had the onset of type 2 diabetes prior to that of hypertension, and 1403 native Kuwaiti hypertensive individuals with no incidence of diabetes. These participants have been regularly monitored for BMI, glycated haemoglobin and blood pressure measurements. Mean variance in BMI per individual over the period from registration is seen to be low.
main outcome measuresAssociation between age at onset of hypertension and BMI (as measured at hypertension diagnosis); HRs for developing hypertension.
resultsRisk of hypertension increases with obesity levels, and is higher in patients with diabetes than in patients without diabetes but of similar obesity levels. Age at onset of hypertension is inversely related to BMI; this relationship is seen to be stronger in men compared to women (slope estimate in men, -0.62 years per unit increase in BMI; in women -0.18) and in individuals (particularly women) with diabetes compared to those without (slope estimate in women, -0.39 vs -0.18, p<0.001; in men -0.66 vs -0.62; p=0.66).
conclusionsThe observation that the presence of diabetes doubles the slope of inverse relationship between hypertension onset age and BMI in women (while the slope is high in men irrespective of diabetes status) leads to a possible proposition that pre-existing diabetes narrows down sex-specific differences in the impact of obesity on blood pressure.
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