Evidence map›Paper›PMID 26044672›Full record

ReviewDrug delivery and translational research2015

Microneedle-based drug and vaccine delivery via nanoporous microneedle arrays.

Koen van der Maaden, Regina Luttge, Pieter Jan Vos, Joke Bouwstra, Gideon Kersten, Ivo Ploemen

Abstract readReview
In one paragraph

Review in Drug delivery and translational research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Koen van der MaadenMyLife Technologies, Enschede, The Netherlands, maaden@mylifetechnologies.nl.
Regina Luttge
Pieter Jan Vos
Joke Bouwstra
Gideon Kersten
Ivo Ploemen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the literature, several types of microneedles have been extensively described. However, porous microneedle arrays only received minimal attention. Hence, only little is known about drug delivery via these microneedles. However, porous microneedle arrays may have potential for future microneedle-based drug and vaccine delivery and could be a valuable addition to the other microneedle-based drug delivery approaches. To gain more insight into porous microneedle technologies, the scientific and patent literature is reviewed, and we focus on the possibilities and constraints of porous microneedle technologies for dermal drug delivery. Furthermore, we show preliminary data with commercially available porous microneedles and describe future directions in this field of research.

Indexed as

NanoporesNeedlesDrug Delivery SystemsEquipment DesignHumansMicroinjectionsPermeabilityPharmaceutical PreparationsSkinVaccinesPharmaceutical PreparationsVaccines

Identifiers

PMID26044672
PMCPMC4529475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.