Evidence map›Paper›PMID 26043843›Full record

ArticleBMC research notes2015

Prescribing preferences in rapid tranquillisation: a survey in Belgian psychiatrists and emergency physicians.

Chris Bervoets, Ella Roelant, Jürgen De Fruyt, Hella Demunter, Barry Dekeyser, Leen Vandenbussche, Koen Titeca, Guido Pieters, Bernard Sabbe, Manuel Morrens

Abstract readComparative Study
In one paragraph

Article in BMC research notes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Prescription Patterns of Intramuscular Medication for Psychomotor Agitation: A Survey of Italian Psychiatrists.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chris BervoetsFaculteit geneeskunde en gezondheidswetenschappen, Collaborative Antwerp Psychiatric Research Institute (CAPRI), University of Antwerp, Antwerp, Belgium. chris.bervoets@uantwerpen.be.
Ella RoelantFaculteit geneeskunde en gezondheidswetenschappen, Collaborative Antwerp Psychiatric Research Institute (CAPRI), University of Antwerp, Antwerp, Belgium. ella.roelant@uantwerpen.be.
Jürgen De FruytAZ Sint Jan Brugge-Oostende AV, Brugge, Belgium. jurgen.defruyt@azbrugge.be.
Hella DemunterUPC KULeuven, Campus Kortenberg, Louvain, Belgium. hella.demunter@uc-kortenberg.be.
Barry DekeyserAZ Herentals, Herentals, Belgium. barry.dekeyser@telenet.be.
Leen VandenbusscheUZ Gent, Ghent, Belgium. leen.vandenbussche@ugent.be.
Koen TitecaAZ Groeninge, Kortrijk, Belgium. koen.titeca@azgroeninge.be.
Guido PietersFaculteit geneeskunde en gezondheidswetenschappen, Collaborative Antwerp Psychiatric Research Institute (CAPRI), University of Antwerp, Antwerp, Belgium. guido.pieters@uc-kortenberg.be.
Bernard SabbeFaculteit geneeskunde en gezondheidswetenschappen, Collaborative Antwerp Psychiatric Research Institute (CAPRI), University of Antwerp, Antwerp, Belgium. bernard.sabbe@uantwerpen.be.
Manuel MorrensFaculteit geneeskunde en gezondheidswetenschappen, Collaborative Antwerp Psychiatric Research Institute (CAPRI), University of Antwerp, Antwerp, Belgium. manuel.morrens@uantwerpen.be.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe pharmacotherapeutic management of agitation is a common clinical challenge. Pharmacotherapy is frequently used, the use of published guidelines is not known. The purpose of this study was twofold; to describe the prescribing patterns of psychiatrists and emergency physicians and to evaluate to which extent guidelines are used.

methodsA cross-sectional survey in the Dutch-speaking part of Belgium is carried out in 39 psychiatric hospitals, 11 psychiatric wards of a general hospital and 61 emergency departments. All physicians are asked for demographic information, their prescribing preferences, their use of guidelines and the type of monitoring (effectiveness, safety). For the basic demographic data and prescription preferences descriptive statistics are given. For comparing prescribing preferences of the drug between groups Chi square tests (or in case of low numbers Fisher's exact test) were performed. Mc Nemar test for binomial proportions for matched-pair data was performed to see if the prescription preferences of the participants differ between secluded and non-secluded patients.

results550 psychiatrist and emergency physicians were invited. The overall response rate was 20% (n = 108). The number 1 preferred medication classes were antipsychotics (59.3%) and benzodiazepines (40.7%). In non-secluded patients, olanzapine (22.2%), lorazepam (21.3%) and clotiapine (19.4%) were most frequently picked as number 1 choice drug. In secluded patients, clotiapine (21.3%), olanzapine (21.3%) and droperidol (14.8%) were the three most frequently chosen number 1 preferred drugs. Between-group comparisons show that emergency physicians prefer benzodiazepines significantly more than psychiatrists do. Zuclopenthixol and olanzapine show a particular profile in both groups of physicians. Polypharmacy is more frequently used in secluded patients. Published guidelines and safety or outcome monitoring are rarely used.

conclusionsOur results show that prescription practice in Flanders (Belgium) in acute agitation shows a complex relationship with published guidelines. Prescription preferences differ accordingly to medical specialty. These findings should be taken into account in future research.

Indexed as

Attitude of Health PersonnelBelgiumChi-Square DistributionCross-Sectional StudiesDrug Utilization ReviewEmergency Service, HospitalEmergency Services, PsychiatricGuideline AdherenceHealth Care SurveysHealth Knowledge, Attitudes, PracticeHumansPhysiciansPractice Guidelines as TopicPractice Patterns, Physicians'Psychomotor AgitationSpecializationTranquilizing Agents

Identifiers

PMID26043843
PMCPMC4467636

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.