ArticleParasites & vectors2015
Infection and exposure to vector-borne pathogens in rural dogs and their ticks, Uganda.
Article in Parasites & vectors, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Anaplasma platys beyond canines: a systematic review of host range, phylogenetic relatedness, and knowledge gaps in Africa.Parasites & vectors · 2026Pooled it
- Data release: targeted systematic literature search for tick and tick-borne pathogen distributions in six countries in sub-Saharan Africa from 1901 to 2020.Parasites & vectors · 2024Pooled it
- The Global Molecular Prevalence ofTransboundary and emerging diseases · 2023Pooled it
- Vector-borne pathogen profiling and phylogeny of ticks infesting domestic dogs in Chad, Africa, using targeted next-generation sequencing and DNA barcoding.Parasites & vectors · 2026Article
- Seroepidemiology of Rickettsia conorii in dogs in Portugal: a comprehensive 12-year retrospective study (2013-2024).Parasites & vectors · 2025Article
- Canine Babesiosis Caused by LargeAnimals : an open access journal from MDPI · 2023Review
- Wide distribution of Mediterranean and African spotted fever agents and the first identification of Israeli spotted fever agent in ticks in Uganda.PLoS neglected tropical diseases · 2023Article
- Co-infection patterns of vector-borne zoonotic pathogens in owned free-ranging dogs in central Chile.Veterinary research communications · 2023Article
- Distribution and Prevalence ofMicroorganisms · 2023Review
- Epidemiological Survey on Tick-Borne Pathogens with Zoonotic Potential in Dog Populations of Southern Ethiopia.Tropical medicine and infectious disease · 2023Article
- Filarial nematodes in domestic dogs and mosquitoes (Diptera: Culicidae) from semi-rural areas in Central Chile.Frontiers in veterinary science · 2023Article
- Dried Blood Spots technology for veterinary applications and biological investigations: technical aspects, retrospective analysis, ongoing status and future perspectives.Veterinary research communications · 2022Review
- Epidemiology, Diagnosis, and Control of Canine Infectious Cyclic Thrombocytopenia and Granulocytic Anaplasmosis: Emerging Diseases of Veterinary and Public Health Significance.Veterinary sciences · 2021Review
- Ticks and Tick-Borne Pathogens Associated with Dromedary Camels (Microorganisms · 2021Article
- HemotropicPathogens (Basel, Switzerland) · 2021Article
- Seroprevalence and associated risk factors for vector-borne pathogens in dogs from Egypt.Parasites & vectors · 2021Article
- Molecular investigation and phylogeny of species of the Anaplasmataceae infecting animals and ticks in Senegal.Parasites & vectors · 2019Article
- Bartonella infections in cats and dogs including zoonotic aspects.Parasites & vectors · 2018Review
- Serological and molecular detection of spotted fever group Rickettsia in a group of pet dogs from Luanda, Angola.Parasites & vectors · 2017Article
- African Tick-Bite Fever in Traveler Returning to Slovenia from Uganda.Emerging infectious diseases · 2016Article
Corrections and comments
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Authors and funding
15 authors at 9 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn rural parts of Africa, dogs live in close association with humans and livestock, roam freely, and usually do not receive prophylactic measures. Thus, they are a source of infectious disease for humans and for wildlife such as protected carnivores. In 2011, an epidemiological study was carried out around three conservation areas in Uganda to detect the presence and determine the prevalence of vector-borne pathogens in rural dogs and associated ticks to evaluate the risk that these pathogens pose to humans and wildlife.
methodsSerum samples (n = 105), blood smears (n = 43) and blood preserved on FTA cards (n = 38) and ticks (58 monospecific pools of Haemaphysalis leachi and Rhipicephalus praetextatus including 312 ticks from 52 dogs) were collected from dogs. Dog sera were tested by indirect immunofluorescence to detect the presence of antibodies against Rickettsia conorii and Ehrlichia canis. Antibodies against R. conorii were also examined by indirect enzyme immunoassay. Real time PCR for the detection of Rickettsia spp., Anaplasmataceae, Bartonella spp. and Babesia spp. was performed in DNA extracted from FTA cards and ticks.
results99% of the dogs were seropositive to Rickettsia spp. and 29.5% to Ehrlichia spp. Molecular analyses revealed that 7.8% of the blood samples were infected with Babesia rossi, and all were negative for Rickettsia spp. and Ehrlichia spp. Ticks were infected with Rickettsia sp. (18.9%), including R. conorii and R. massiliae; Ehrlichia sp. (18.9%), including E. chaffeensis and Anaplasma platys; and B. rossi (1.7%). Bartonella spp. was not detected in any of the blood or tick samples.
conclusionsThis study confirms the presence of previously undetected vector-borne pathogens of humans and animals in East Africa. We recommend that dog owners in rural Uganda be advised to protect their animals against ectoparasites to prevent the transmission of pathogens to humans and wildlife.
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