ArticleThe Kaohsiung journal of medical sciences2015
Anti-inflammatory effects of bamboo salt and sodium fluoride in human gingival fibroblasts--An in vitro study.
Article in The Kaohsiung journal of medical sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Antibacterial effect of an herbal toothpaste containing Bamboo salt: a randomized double-blinded controlled clinical trial.BMC oral health · 2022Trial
- Comparison of the cytotoxic and apoptotic effects of mouthwashes containing different active ingredients on human gingival fibroblasts and their antimicrobial efficacy.BMC oral health · 2026Article
- Article
- Review
- Antioxidant and anti-inflammatory effects of solar salt brined kimchi.Food science and biotechnology · 2023Article
- Biphasic Functions of Sodium Fluoride (NaF) in Soft and in Hard Periodontal Tissues.International journal of molecular sciences · 2022Review
- Supportive Home Remedies for Orofacial Pain during the Coronavirus Disease 2019 Pandemic: Their Value and Limitations.International journal of dentistry · 2022Review
- Environmental Factors Impacting Bone-Relevant Chemokines.Frontiers in endocrinology · 2017Article
- The effect of natural reducing agents on push-out bond strength of AH plus and BioRoot RCS to sodium hypochlorite treated root dentin.Journal of conservative dentistry : JCDArticle
- Evaluating Therapeutic Efficacy of Bamboo Salt Mouthwash Compared to Benzydamine Hydrochloride Mouthwash for Recurrent Aphthous Ulceration: A Double-blind Randomized Clinical Trial.Journal of research in pharmacy practiceArticle
- Effect of proanthocyanidin and bamboo salt on the push-out bond strength of an epoxy resin sealer to sodium hypochlorite-treated root dentin: AnJournal of conservative dentistry : JCDArticle
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dental caries preventive agents, such as sodium fluoride (NaF) and bamboo salt (BS), are known to cause cellular growth that is characterized by morphological and gene expression changes. This study was designed to investigate the dual effect of NaF and BS on interleukin (IL)-1β-induced gingival inflammation. Under in vitro experimental conditions, exposure to a subcytotoxic dose of IL-1β enhanced human gingival fibroblast inflammation, as characterized by increased levels of inflammation-associated proteins. A combination of NaF and BS significantly protected fibroblasts from IL-1β-induced cellular deterioration. Exposure to NaF and BS induced the cell growth and no changes in viability were found with the Lactate Dehydrogenase Assay (LDH) assay at the NaF and BS concentration analyzed. Molecular analysis demonstrated that NaF and BS increased resistance to inflammation by reduction of IL-1β, IL-8, and tumor necrosis factor (TNF)-α production. In addition, NaF and BS decreased the expression of IL-1β, IL-8, and TNF-α mRNA in IL-1β-induced human gingival fibroblast cells. The study identifies a new role for NaF and BS in the IL-1β-induced inflammation of gingival fibroblasts and provides a potential target for gingival protection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.