Evidence map›Paper›PMID 26042037›Full record

ArticleFrontiers in pharmacology2015

The acute and sub-chronic effects of cocoa flavanols on mood, cognitive and cardiovascular health in young healthy adults: a randomized, controlled trial.

Laura A Massee, Karin Ried, Matthew Pase, Nikolaj Travica, Jaesshanth Yoganathan, Andrew Scholey, Helen Macpherson, Greg Kennedy, Avni Sali, Andrew Pipingas

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 5 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 5 syntheses or guidelines pooled it, 89 citations in OpenAlex.

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  5. Effect of cocoa on blood pressure.The Cochrane database of systematic reviews · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Laura A MasseeCentre for Human Psychopharmacology, Swinburne University of Technology Melbourne, VIC, Australia.
Karin RiedNational Institute of Integrative Medicine Melbourne, VIC, Australia.
Matthew PaseCentre for Human Psychopharmacology, Swinburne University of Technology Melbourne, VIC, Australia ; Department of Neurology, Boston University School of Medicine Boston, MA, USA.
Nikolaj TravicaNational Institute of Integrative Medicine Melbourne, VIC, Australia.
Jaesshanth YoganathanCentre for Human Psychopharmacology, Swinburne University of Technology Melbourne, VIC, Australia.
Andrew ScholeyCentre for Human Psychopharmacology, Swinburne University of Technology Melbourne, VIC, Australia.
Helen MacphersonCentre for Human Psychopharmacology, Swinburne University of Technology Melbourne, VIC, Australia.
Greg KennedyCentre for Human Psychopharmacology, Swinburne University of Technology Melbourne, VIC, Australia.
Avni SaliNational Institute of Integrative Medicine Melbourne, VIC, Australia.
Andrew PipingasCentre for Human Psychopharmacology, Swinburne University of Technology Melbourne, VIC, Australia.
Swinburne University of Technology · AUNational Institute of Integrative Medicine · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cocoa supplementation has been associated with benefits to cardiovascular health. However, cocoa's effects on cognition are less clear. A randomized, placebo-controlled, double-blind clinical trial (n = 40, age M = 24.13 years, SD = 4.47 years) was conducted to investigate the effects of both acute (same-day) and sub-chronic (daily for four-weeks) 250 mg cocoa supplementation on mood and mental fatigue, cognitive performance and cardiovascular functioning in young, healthy adults. Assessment involved repeated 10-min cycles of the Cognitive Demand Battery (CDB) encompassing two serial subtraction tasks (Serial Threes and Sevens), a Rapid Visual Information Processing task, and a mental fatigue scale over the course of half an hour. The Swinburne University Computerized Cognitive Assessment Battery (SUCCAB) was also completed to evaluate cognition. Cardiovascular function included measuring both peripheral and central blood pressure and cerebral blood flow. At the acute time point, consumption of cocoa significantly improved self-reported mental fatigue and performance on the Serial Sevens task in cycle one of the CDB. No other significant effects were found. This trial was registered with the Australian and New Zealand Clinical Trial Registry (Trial ID: ACTRN12613000626763). Accessible via http://www.anzctr.org.au/TrialSearch.aspx?searchTxt=ACTRN12613000626763&ddlSearch=Registered.

Indexed as

cardiovascularchocolatecocoacognitionflavanolsmental fatiguemood

Identifiers

PMID26042037
PMCPMC4438591
OpenAlexW1564543077

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.