ArticleFrontiers in behavioral neuroscience2015
What does spatial alternation tell us about retrosplenial cortex function?
Article in Frontiers in behavioral neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- The retrosplenial cortical role in delayed spatial alternation.Neurobiology of learning and memory · 2024Article
- FOS mapping reveals two complementary circuits for spatial navigation in mouse.Scientific reports · 2024Article
- The Retrosplenial Cortical Role in Delayed Spatial Alternation.bioRxiv : the preprint server for biology · 2024Article
- Coordinated Interactions between the Hippocampus and Retrosplenial Cortex in Spatial Memory.Research (Washington, D.C.) · 2024Article
- Melatonin reduces β-amyloid accumulation and improves short-term memory in streptozotocin-induced sporadic Alzheimer's disease model.IBRO neuroscience reports · 2023Article
- FOXG1 drives transcriptomic networks to specify principal neuron subtypes during the development of the medial pallium.Science advances · 2023Article
- Aberrant miR-339-5p/neuronatin signaling causes prodromal neuronal calcium dyshomeostasis in mutant presenilin mice.The Journal of clinical investigation · 2022Article
- Neural basis of topographical disorientation in the primate posterior cingulate gyrus based on a labeled graph.AIMS neuroscience · 2022Article
- Retrosplenial cortex in spatial memory: focus on immediate early genes mapping.Molecular brain · 2021Review
- Post-Training Sleep Modulates Topographical Relearning-Dependent Resting State Activity.Brain sciences · 2021Article
- Dual-Factor Representation of the Environmental Context in the Retrosplenial Cortex.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- The retrosplenial cortex and long-term spatial memory: from the cell to the network.Current opinion in behavioral sciences · 2020Review
- Long-range inhibitory intersection of a retrosplenial thalamocortical circuit by apical tuft-targeting CA1 neurons.Nature neuroscience · 2019Article
- The retrosplenial cortical role in encoding behaviorally significant cues.Behavioral neuroscience · 2018Review
- When is the rat retrosplenial cortex required for stimulus integration?Behavioral neuroscience · 2018Article
- Cholinergic modulation of spatial learning, memory and navigation.The European journal of neuroscience · 2018Review
- Network supporting contextual fear learning after dorsal hippocampal damage has increased dependence on retrosplenial cortex.PLoS computational biology · 2018Article
- Disentangling the Contribution of Spatial Reference Frames to Executive Functioning in Healthy and Pathological Aging: An Experimental Study with Virtual Reality.Sensors (Basel, Switzerland) · 2018Article
- Retrosplenial cortex and its role in spatial cognition.Brain and neuroscience advances · 2018Review
- The rat retrosplenial cortex as a link for frontal functions: A lesion analysis.Behavioural brain research · 2017Article
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5 authors.
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Abstract
The retrosplenial cortex supports navigation, but there are good reasons to suppose that the retrosplenial cortex has a very different role in spatial memory from that of the hippocampus and anterior thalamic nuclei. For example, retrosplenial lesions appear to have little or no effect on standard tests of spatial alternation. To examine these differences, the current study sought to determine whether the retrosplenial cortex is important for just one spatial cue type (e.g., allocentric, directional or intra-maze cues) or whether the retrosplenial cortex helps the animal switch between competing spatial strategies or competing cue types. Using T-maze alternation, retrosplenial lesion rats were challenged with situations in which the available spatial information between the sample and test phases was changed, so taxing the interaction between different cue types. Clear lesion deficits emerged when intra- and extra-maze cues were placed in conflict (by rotating the maze between the sample and choice phases), or when the animals were tested in the dark in a double-maze. Finally, temporary inactivation of the retrosplenial cortex by muscimol infusions resulted in a striking deficit on standard T-maze alternation, indicating that, over time, other sites may be able to compensate for the loss of the retrosplenial cortex. This pattern of results is consistent with the impoverished use of both allocentric and directional information, exacerbated by an impaired ability to switch between different cue types.
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