Evidence map›Paper›PMID 26041362›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2015

Nocturnal Hypertension Correlates Better With Target Organ Damage in Patients With Chronic Kidney Disease than a Nondipping Pattern.

Cheng Wang, Wen-Jie Deng, Wen-Yu Gong, Jun Zhang, Qun-Zi Zhang, Zeng Chun Ye, Tanqi Lou

3 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03603938 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Effect of Potassium Losartan With Bedtime Dosing on Chronic Kidney Disease Patients With Nondipping Blood Pressure Pattern

TypeinterventionalSponsorFifth Affiliated Hospital, Sun Yat-Sen UniversityRan2018 to 2023Enrolled189ConditionsChronic Kidney Disease PatientsArmspotassium losartan
NCT03604003 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Prognostic Effect of Isolated Nocturnal Hypertension Pattern With Nondialysis CKD

TypeinterventionalSponsorFifth Affiliated Hospital, Sun Yat-Sen UniversityRan2018 to 2023Enrolled252ConditionsChronic Kidney DiseaseArmspotassium losartan
NCT03718585 unknown statusnot on this mapstarted 2018, after this paper: background citation

Whole Exome Sequencing Analysis Project in Chronic Kidney Disease Patients With Nocturnal Hypertension

Typeobservational_patient_registrySponsorFifth Affiliated Hospital, Sun Yat-Sen UniversityRan2018 to 2022Enrolled4,000ConditionsHypertension, NephropathyArmswhole exome sequencing analysis
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Prognostic value of nighttime blood pressure in patients with chronic kidney disease.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Article
  8. Article
  9. Article
  10. Is systolic blood pressure decrease with age in patients with Parkinson's disease?Journal of clinical hypertension (Greenwich, Conn.) · 2021
    Article
  11. Article
  12. Clinical applications for out-of-office blood pressure monitoring.Therapeutic advances in chronic disease · 2020
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Cheng WangDivision of Nephrology, Department of Medicine, Third Affiliated Hosptial of Sun Yat-Sen University, Guangzhou, Guangdong, China.
Wen-Jie DengDivision of Nephrology, Department of Medicine, Third Affiliated Hosptial of Sun Yat-Sen University, Guangzhou, Guangdong, China.
Wen-Yu GongDivision of Nephrology, Department of Medicine, Third Affiliated Hosptial of Sun Yat-Sen University, Guangzhou, Guangdong, China.
Jun ZhangDivision of Nephrology, Department of Medicine, Third Affiliated Hosptial of Sun Yat-Sen University, Guangzhou, Guangdong, China.
Qun-Zi ZhangDivision of Nephrology, Department of Medicine, Third Affiliated Hosptial of Sun Yat-Sen University, Guangzhou, Guangdong, China.
Zeng Chun YeDivision of Nephrology, Department of Medicine, Third Affiliated Hosptial of Sun Yat-Sen University, Guangzhou, Guangdong, China.
Tanqi LouDivision of Nephrology, Department of Medicine, Third Affiliated Hosptial of Sun Yat-Sen University, Guangzhou, Guangdong, China.
Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Both nocturnal hypertension and nondipping pattern are associated with target organ damages (TODs); however, no data exist with respect to Chinese patients with chronic kidney disease (CKD). The authors recruited 1322 patients with CKD admitted to our hospital division and referred with data in this cross-sectional study. Patients with nocturnal systolic hypertension had a lower estimated glomerular filtration rate (eGFR) and higher left ventricular mass index (LVMI) and carotid intima-media thickness (cIMT) compared with patients with normal nocturnal systolic blood pressure (SPB; all, P<.001), while patients in the dipper and nondipper groups had similar levels of eGFR, LVMI, and cIMT when the patients had a similar nocturnal SBP. Factorial-designed analysis of variance indicated that the main effect of nocturnal SBP was significant for all TOD differences (all, P<.001), but no significance existed with respect to the main effect of the dipper pattern and an interaction between the two factors (all, P>.05). Nocturnal systolic hypertension, rather than nondipping pattern, was an independent risk factor for TOD in CKD patients. Nocturnal hypertension, rather than a nondipping pattern, was better associated with TOD in CKD patients.

Indexed as

AdultBlood PressureBlood Pressure Monitoring, AmbulatoryCarotid ArteriesCarotid Intima-Media ThicknessChinaCircadian RhythmCross-Sectional StudiesFemaleGlomerular Filtration RateHumansHypertensionHypertrophy, Left VentricularMaleMiddle AgedPrevalence

Identifiers

PMID26041362
PMCPMC8031545
OpenAlexW1503387441

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.