Trial reportThe American journal of clinical nutrition2015
Validation of an inexpensive and accurate mathematical method to measure long-term changes in free-living energy intake.
Trial report in The American journal of clinical nutrition, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.
- Do eating behavior traits predict energy intake and body mass index? A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023Pooled it
- Glucagon-like peptide-1/glucagon receptor agonism associates with reduced metabolic adaptation and higher fat oxidation: A randomized trial.Obesity (Silver Spring, Md.) · 2023Trial
- Challenges in defining successful adherence to calorie restriction goals in humans: Results from CALERIE™ 2.Experimental gerontology · 2022Trial
- Effects of caloric restriction on human physiological, psychological, and behavioral outcomes: highlights from CALERIE phase 2.Nutrition reviews · 2021Trial
- Effects of Time-Restricted Eating on Weight Loss and Other Metabolic Parameters in Women and Men With Overweight and Obesity: The TREAT Randomized Clinical Trial.JAMA internal medicine · 2020Trial
- How Strongly Does Appetite Counter Weight Loss? Quantification of the Feedback Control of Human Energy Intake.Obesity (Silver Spring, Md.) · 2016Trial
- Trial
- A bedside-to-outside model of human nutrition research.Cell metabolism · 2026Review
- Multilevel metabolic adaptation to exercise training.Communications medicine · 2026Article
- A Model to Assess the Costs and Consequences of Changes in Diet and Nutrition From Potential Population-Wide Policies: The Microsimulation of Nutrition, Diabetes, and Cardiovascular Disease (MONDAC).Preventing chronic disease · 2025Article
- Predictive equation helps estimate misreporting of energy intakes in dietary surveys.Nature food · 2025Article
- Article
- Total energy expenditure as assessed by doubly labeled water and all-cause mortality in a cohort of postmenopausal women.The American journal of clinical nutrition · 2023Article
- Brown Adipose Tissue-A Translational Perspective.Endocrine reviews · 2023Review
- Predicting energy intake in adults who are dieting and exercising.International journal of obesity (2005) · 2022Article
- Immune and non-immune functions of adipose tissue leukocytes.Nature reviews. Immunology · 2022Review
- An objective measure of energy intake using the principle of energy balance.International journal of obesity (2005) · 2021Review
- Dietary interventions for obesity: clinical and mechanistic findings.The Journal of clinical investigation · 2021Review
- Evidence-Based Digital Tools for Weight Loss Maintenance: The NoHoW Project.Obesity facts · 2021Article
- The H2020 "NoHoW Project": A Position Statement on Behavioural Approaches to Longer-Term Weight Management.Obesity facts · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundAccurate measurement of free-living energy intake (EI) over long periods is imperative for understanding obesity and its treatment. Unfortunately, traditional methods rely on self-report and are notoriously inaccurate. Although EI can be indirectly estimated by the intake-balance method, this technique is prohibitively labor-intensive and expensive, requiring repeated measures of energy expenditure via doubly labeled water (DLW) along with multiple dual-energy X-ray absorptiometry (DXA) scans to measure changes in body energy stores.
objectiveOur objective was to validate a mathematical method to measure long-term changes in free-living energy intake.
designWe measured body weight and EI changes (ΔEI) over 4 time intervals by using the intake-balance method in 140 individuals who underwent 2 y of caloric restriction as part of the Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy study. We compared the ΔEI values calculated by using DLW/DXA with those obtained by using a mathematical model of human metabolism whose only inputs were the initial demographic information and repeated body weight data.
resultsThe mean ΔEI values calculated by the model were within 40 kcal/d of the DLW/DXA method throughout the 2-y study. For individual subjects, the overall root mean square deviation between the model and DLW/DXA method was 215 kcal/d, and most of the model-calculated ΔEI values were within 132 kcal/d of the DLW/DXA method.
conclusionsAccurate and inexpensive estimates of ΔEI that are comparable to the DLW/DXA method can be obtained by using a mathematical model and repeated body weight measurements.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.