ReviewProceedings of the National Academy of Sciences of the United States of America2015
Signatures of host/symbiont genome coevolution in insect nutritional endosymbioses.
Review in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.
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Who cites it
79 citing papers in PubMed, 156 citations in OpenAlex.
- Intrahost mutational dynamics parallel long-term genome evolution in endosymbionts.Molecular biology and evolution · 2026Article
- Review
- Cellular remodeling of ovarian follicular epithelial cells transmits an obligate nutritional endosymbiont in a scale insect.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Evidence of Relaxed Selection in the Mitochondrial Genomes of Phototrophic Paulinella Lineages.Genome biology and evolution · 2026Article
- Genomes of NBMC genomics · 2026Article
- Splicing regulation and intron evolution in the short-intron ciliate model of endosymbiosis Paramecium bursaria.Nucleic acids research · 2026Article
- Characterizing a Novel Symbiopectobacterium purcellii MEX Strain at the Early Stages of Establishing a Symbiotic Relationship.Genome biology and evolution · 2026Article
- Occurrence and temporal dynamics of denitrifying protist endosymbionts in the wastewater microbiome.ISME communications · 2025Article
- Biotype and host relatedness influence the composition of bacterial microbiomes inFrontiers in microbiology · 2025Article
- A complete DNA repair system assembled by two endosymbionts restores heat tolerance of the insect host.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Endosymbioses Have Shaped the Evolution of Biological Diversity and Complexity Time and Time Again.Genome biology and evolution · 2024Review
- Stochasticity, determinism, and contingency shape genome evolution of endosymbiotic bacteria.Nature communications · 2024Article
- Modeling endosymbioses: Insights and hypotheses from theoretical approaches.PLoS biology · 2024Article
- Unveiling microbial guilds and symbiotic relationships in Antarctic sponge microbiomes.Scientific reports · 2024Article
- Endosymbiont Tremblaya phenacola influences the reproduction of cotton mealybugs by regulating the mechanistic target of rapamycin pathway.The ISME journal · 2024Article
- Article
- Significant role of symbiotic bacteria in the blood digestion and reproduction ofISME communications · 2024Article
- Phylosymbiosis: The Eco-Evolutionary Pattern of Insect-Symbiont Interactions.International journal of molecular sciences · 2023Review
- Co-option of a conserved host glutamine transporter facilitates aphid/Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Starving the Beast: Limiting Coenzyme A Biosynthesis to Prevent Disease and Transmission in Malaria.International journal of molecular sciences · 2023Review
19 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The role of symbiosis in bacterial symbiont genome evolution is well understood, yet the ways that symbiosis shapes host genomes or more particularly, host/symbiont genome coevolution in the holobiont is only now being revealed. Here, we identify three coevolutionary signatures that characterize holobiont genomes. The first signature, host/symbiont collaboration, arises when completion of essential pathways requires host/endosymbiont genome complementarity. Metabolic collaboration has evolved numerous times in the pathways of amino acid and vitamin biosynthesis. Here, we highlight collaboration in branched-chain amino acid and pantothenate (vitamin B5) biosynthesis. The second coevolutionary signature is acquisition, referring to the observation that holobiont genomes acquire novel genetic material through various means, including gene duplication, lateral gene transfer from bacteria that are not their current obligate symbionts, and full or partial endosymbiont replacement. The third signature, constraint, introduces the idea that holobiont genome evolution is constrained by the processes governing symbiont genome evolution. In addition, we propose that collaboration is constrained by the expression profile of the cell lineage from which endosymbiont-containing host cells, called bacteriocytes, are derived. In particular, we propose that such differences in bacteriocyte cell lineage may explain differences in patterns of host/endosymbiont metabolic collaboration between the sap-feeding suborders Sternorrhyncha and Auchenorrhynca. Finally, we review recent studies at the frontier of symbiosis research that are applying functional genomic approaches to characterization of the developmental and cellular mechanisms of host/endosymbiont integration, work that heralds a new era in symbiosis research.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.