ArticlePLoS neglected tropical diseases2015
Human-Mediated Marine Dispersal Influences the Population Structure of Aedes aegypti in the Philippine Archipelago.
Article in PLoS neglected tropical diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Trends in dengue research in the Philippines: A systematic review.PLoS neglected tropical diseases · 2019Pooled it
- Changing dynamics of Aedes aegypti invasion and vector-borne disease risk for rural communities in the Peruvian Amazon.PLoS neglected tropical diseases · 2025Article
- Fine-scale adaptive divergence and population genetic structure of Aedes aegypti in Metropolitan Manila, Philippines.Parasites & vectors · 2024Article
- Genetic structure and kdr mutations in Aedes aegypti populations along a road crossing the Amazon Forest in Amapá State, Brazil.Scientific reports · 2023Article
- Genetic Differentiation ofInsects · 2023Article
- Population structure and invasion history ofEvolutionary applications · 2023Article
- Past, present and future distribution of the yellow fever mosquito Aedes aegypti: The European paradox.The Science of the total environment · 2022Article
- Article
- Genetic Diversity among Four Populations ofPathogens (Basel, Switzerland) · 2022Article
- Evidence for serial founder events during the colonization of North America by the yellow fever mosquito,Ecology and evolution · 2022Article
- Population differentiation and intraspecific genetic admixture in twoEcology and evolution · 2022Article
- Novel and Broadly Applicable Microsatellite Markers in Identified Chromosomes of the Philippine Dengue Mosquitoes, Aedes aegypti (Diptera: Culicidae).Journal of medical entomology · 2022Article
- Population Genetic Analysis ofFrontiers in genetics · 2022Article
- A machine-learning approach to map landscape connectivity inProceedings of the National Academy of Sciences of the United States of America · 2021Article
- The influence of roads on the fine-scale population genetic structure of the dengue vector Aedes aegypti (Linnaeus).PLoS neglected tropical diseases · 2021Article
- Sunshine versus gold: The effect of population age on genetic structure of an invasive mosquito.Ecology and evolution · 2020Article
- Fine-scale population genetic structure of dengue mosquito vector, Aedes aegypti, in Metropolitan Manila, Philippines.PLoS neglected tropical diseases · 2020Article
- The genetic structure of Aedes aegypti populations is driven by boat traffic in the Peruvian Amazon.PLoS neglected tropical diseases · 2019Article
- Insecticide resistance status of Aedes aegypti and Aedes albopictus mosquitoes in Papua New Guinea.Parasites & vectors · 2019Article
- Spatiotemporal Heterogeneity in the Distribution of Chikungunya and Zika Virus Case Incidences during their 2014 to 2016 Epidemics in Barranquilla, Colombia.International journal of environmental research and public health · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDengue virus (DENV) is an extraordinary health burden on global scale, but still lacks effective vaccine. The Philippines is endemic for dengue fever, but massive employment of insecticides favored the development of resistance mutations in its major vector, Aedes aegypti. Alternative vector control strategies consist in releasing artificially modified mosquitos in the wild, but knowledge on their dispersal ability is necessary for a successful implementation. Despite being documented that Ae. aegypti can be passively transported for long distances, no study to date has been aimed at understanding whether human marine transportation can substantially shape the migration patterns of this mosquito. With thousands of islands connected by a dense network of ships, the Philippines is an ideal environment to fill this knowledge gap. METHODOLOGY/PRINCIPAL
findingsLarvae of Ae. aegypti from 15 seaports in seven major islands of central-western Philippines were collected and genotyped at seven microsatellite loci. Low genetic structure and considerable gene flow was found in the area. Univariate and multivariate regression analyses suggested that anthropic factors (specifically the amount of processed cargo and human population density) can explain the observed population structure, while geographical distance was not correlated. Interestingly, cargo shipments seem to be more efficient than passenger ships in transporting Ae. aegypti. Bayesian clustering confirmed that Ae. aegypti from busy ports are more genetically similar, while populations from idle ports are relatively structured, regardless of the geographical distance that separates them. CONCLUSIONS/SIGNIFICANCE: The results confirmed the pivotal role of marine human-mediated long-range dispersal in determining the population structure of Ae. aegypti. Hopefully corroborated by further research, the present findings could assist the design of more effective vector control strategies.
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