ArticleEmerging microbes & infections2014
A novel MLST sequence type discovered in the first fatal case of Laribacter hongkongensis bacteremia clusters with the sequence types of other human isolates.
Article in Emerging microbes & infections, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- In vitro and in silico parameters for precise cgMLST typing of Listeria monocytogenes.BMC genomics · 2022Article
- Pan-Genome Analysis ofFrontiers in microbiology · 2022Article
- SARS-CoV-2 surveillance in Italy through phylogenomic inferences based on Hamming distances derived from pan-SNPs, -MNPs and -InDels.BMC genomics · 2021Article
- High Prevalence and Mechanism Associated With Extended Spectrum Beta-Lactamase-Positive Phenotype inFrontiers in microbiology · 2021Article
- ST534: the new sequence type of Corynebacterium diphtheriae causing diphtheria in Jakarta and surrounding areas, IndonesiaTurkish journal of medical sciences · 2020Article
- Identification of Gram negative non-fermentative bacteria: How hard can it be?PLoS neglected tropical diseases · 2019Article
- Clinical Mass Spectrometry in the Bioinformatics Era: A Hitchhiker's Guide.Computational and structural biotechnology journal · 2018Review
- Failure of phylogeny inferred from multilocus sequence typing to represent bacterial phylogeny.Scientific reports · 2017Article
- Definitive Identification of Laribacter hongkongensis Acquired in the United States.Journal of clinical microbiology · 2015Article
- An adult zebrafish model for Laribacter hongkongensis infection: Koch's postulates fulfilled.Emerging microbes & infections · 2014Article
- First Report of Laribacter hongkongensis Peritonitis in Continuous Ambulatory Peritoneal Dialysis.Peritoneal dialysis international : journal of the International Society for Peritoneal DialysisArticle
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Laribacter hongkongensis is a gram-negative, facultative anaerobic, motile, S-shaped, asaccharolytic, urease-positive bacillus in the Neisseriaceae family of β-proteobacteria. To date, all patients with L. hongkongensis infection have survived, including the two patients with L. hongkongensis bacteremia and patients with L. hongkongensis gastroenteritis. In this study, we describe the clinical, microbiological and molecular characterization of the first fatal case associated with L. hongkongensis bacteremia in a patient with colonic carcinoma that metastasized to the liver. The identity of the isolate was confirmed via phenotypic tests and 16S rRNA gene sequencing. Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS), using the Bruker database extended with L. hongkongensis reference strains, also identified the isolate as L. hongkongensis, with a top match score of 2.473. Multilocus sequence typing revealed a new sequence type (ST), and phylogenetic analysis and eBURST demonstrated unambiguously that the ST of the isolate was clustered with two other STs found exclusively in human patients, consistent with the theory that some clones of L. hongkongensis could be more virulent than others. Underlying liver diseases and ascites potentially represent distinct risk factors for invasive L. hongkongensis infection. More widespread use of MALDI-TOF MS for identification and improvements of selective media should facilitate the identification of more cases of L. hongkongensis infection.
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