ReviewEuropean heart journal2015
Fractional flow reserve-guided management in stable coronary disease and acute myocardial infarction: recent developments.
Review in European heart journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01764334 (A Developmental Clinical Study of Management Guided by Coronary Angiography Combined With Fractional Flow Reserve), which is not on this map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Developmental Clinical Study of Management Guided by Coronary Angiography Combined With Fractional Flow Reserve (FFR) Measurement Versus Management Guided by Coronary Angiography Alone(Standard Care) in Patients With Non-ST Elevation MI.
Who cites it
28 citing papers in PubMed.
- Efficacy and safety outcomes of fractional flow reserve in guiding clinical therapy of non-ST-segment elevation myocardial infarction compared with angiography alone in elderly Chinese patients.Clinical interventions in aging · 2016Trial
- Beyond Stenosis: Mechanism-Based Multimodality Imaging and Invasive Coronary Function Testing for Endotype Definition in ANOCA/INOCA.Medicina (Kaunas, Lithuania) · 2026Review
- Performance assessment of computed tomographic angiography fractional flow reserve using deep learning: SMART trial summary.Journal of geriatric cardiology : JGC · 2025Article
- Preliminary outcomes of quantitative flow ratio-guided coronary bypass grafting in primary valve surgery: A propensity score weighted analysis.JTCVS open · 2024Article
- Invasive fractional-flow-reserve prediction by coronary CT angiography using artificial intelligence vs. computational fluid dynamics software in intermediate-grade stenosis.The international journal of cardiovascular imaging · 2024Article
- [Index of microcirculatory resistance is associated with left ventricular remodeling in patients with acute anterior ST-segment elevation myocardial infarction undergoing emergency primary percutaneous coronary intervention].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2024Article
- Nanomedicines as Guardians of the Heart: Unleashing the Power of Antioxidants to Alleviate Myocardial Ischemic Injury.Theranostics · 2024Review
- Impact of antiplatelet therapy on microvascular thrombosis during ST-elevation myocardial infarction.Frontiers in molecular biosciences · 2024Review
- Practical Application of Coronary Physiologic Assessment: Asia-Pacific Expert Consensus Document: Part 2.JACC. Asia · 2023Review
- Comparison of 2D-QCA, 3D-QCA and coronary angiography derived FFR in predicting myocardial ischemia assessed by CZT-SPECT MPI.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Diagnostic performance of computational fluid dynamics (CFD)-based fractional flow reserve (FFR) derived from coronary computed tomographic angiography (CCTA) for assessing functional severity of coronary lesions.Quantitative imaging in medicine and surgery · 2023Article
- Uncertainty quantification of computational fluid dynamics-based predictions for fractional flow reserve and wall shear stress of the idealized stenotic coronary.Frontiers in cardiovascular medicine · 2023Article
- Radiomics analysis enhances the diagnostic performance of CMR stress perfusion: a proof-of-concept study using the Dan-NICAD dataset.Frontiers in cardiovascular medicine · 2023Article
- In Vivo Imaging of Rat Vascularity with FDG-Labeled Erythrocytes.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Influence of lesion and disease subsets on the diagnostic performance of the quantitative flow ratio in real-world patients.Scientific reports · 2021Article
- Investigation of Specific Proteins Related to Different Types of Coronary Atherosclerosis.Frontiers in cardiovascular medicine · 2021Article
- Metformin Activates the AMPK-mTOR Pathway by Modulating lncRNADrug design, development and therapy · 2020Article
- Long Noncoding RNABioMed research international · 2020Article
- An investigation into hemodynamically significant coronary artery lesions predictors assessed by fractional flow reserve: A propensity score matching analysis.Northern clinics of Istanbul · 2020Article
- Acute Coronary Syndrome Mimicking Takotsubo Cardiomyopathy or Takotsubo Cardiomyopathy Mimicking Acute Coronary Syndrome?Case reports in cardiology · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Coronary artery disease (CAD) is a leading global cause of morbidity and mortality, and improvements in the diagnosis and treatment of CAD can reduce the health and economic burden of this condition. Fractional flow reserve (FFR) is an evidence-based diagnostic test of the physiological significance of a coronary artery stenosis. Fractional flow reserve is a pressure-derived index of the maximal achievable myocardial blood flow in the presence of an epicardial coronary stenosis as a ratio to maximum achievable flow if that artery were normal. When compared with standard angiography-guided management, FFR disclosure is impactful on the decision for revascularization and clinical outcomes. In this article, we review recent developments with FFR in patients with stable CAD and recent myocardial infarction. Specifically, we review novel developments in our understanding of CAD pathophysiology, diagnostic applications, prognostic studies, clinical trials, and clinical guidelines.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.