Observational studyJournal of the Academy of Nutrition and Dietetics2015
Bone Mineral Density and Protein-Derived Food Clusters from the Framingham Offspring Study.
Observational study in Journal of the Academy of Nutrition and Dietetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Dietary Patterns, Bone Mineral Density, and Risk of Fractures: A Systematic Review and Meta-Analysis.Nutrients · 2018Pooled it
- The Prevalence and Risk Factors of Low Bone Mineral Density in the Population of the Abay Region of Kazakhstan.International journal of environmental research and public health · 2024Article
- Maternal Dietary Protein Patterns and Neonatal Anthropometrics: A Prospective Study with Insights from NMR Metabolomics in Amniotic Fluid.Metabolites · 2023Article
- Genetic Risk for Osteoporosis and the Benefit of Adherence to Healthy Lifestyles.International journal of public health · 2022Article
- Mediterranean diet adherence and dietary calcium intake in a group of pregnant women: Results of an Italian survey.Food science & nutrition · 2021Article
- Review
- The Mediterranean Diet in Osteoporosis Prevention: An Insight in a Peri- and Post-Menopausal Population.Nutrients · 2021Observational
- Identification of Dish-Based Dietary Patterns for Breakfast, Lunch, and Dinner and Their Diet Quality in Japanese Adults.Nutrients · 2020Article
- Dietary Advanced Glycation End-Products (dAGEs) Intake and Bone Health: A Cross-Sectional Analysis in the Rotterdam Study.Nutrients · 2020Article
- Dietary Approaches to Stop Hypertension, Mediterranean, and Alternative Healthy Eating indices are associated with bone health among Puerto Rican adults from the Boston Puerto Rican Osteoporosis Study.The American journal of clinical nutrition · 2020Article
- Prevalence of Osteoporosis and Low Bone Mass Among Puerto Rican Older Adults.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2018Article
- Vegetarian-style dietary pattern during adolescence has long-term positive impact on bone from adolescence to young adulthood: a longitudinal study.Nutrition journal · 2018Article
- Patterns of Protein Food Intake Are Associated with Nutrient Adequacy in the General French Adult Population.Nutrients · 2018Article
- Association between dietary protein intake and type 2 diabetes varies by dietary pattern.Diabetology & metabolic syndrome · 2018Article
- Association of eating out with bone density in Taiwan.Public health nutrition · 2017Article
- Associations of Baltic Sea and Mediterranean dietary patterns with bone mineral density in elderly women.Public health nutrition · 2017Article
- Protein intake and risk of hip fractures in postmenopausal women and men age 50 and older.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017Article
- Dietary protein is associated with musculoskeletal health independently of dietary pattern: the Framingham Third Generation Study.The American journal of clinical nutrition · 2017Article
- Current Evidence on the Association of Dietary Patterns and Bone Health: A Scoping Review.Advances in nutrition (Bethesda, Md.) · 2017Article
- Adherence to the Mediterranean diet is associated with a higher BMD in middle-aged and elderly Chinese.Scientific reports · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundDietary protein is beneficial to bone health; however, dietary patterns of protein intake and their relationship with bone mineral density (BMD) have not been evaluated.
objectiveTo examine the relationship of dietary protein food clusters with BMD at the femoral neck, trochanter, total femur, and lumbar spine among middle-aged and older men and women.
designCross-sectional study. PARTICIPANTS AND
settingTwo thousand seven hundred fifty-eight community-dwelling individuals from the Framingham Offspring Study.
methodsBMD was measured by Lunar DPX-L (Lunar Radiation Corporation) in 1996-2001. Dietary intakes were estimated using the Willett food frequency questionnaire in either 1995-1998 or 1998-2001, and the exam closest to a participant's BMD measurement was used. Cluster analysis (FASTCLUS procedure, k-means method) was used to classify participants into groups, determined by major sources of protein. Generalized linear regression was used to compare adjusted least-squares mean BMD across protein food clusters for all pairwise comparisons.
resultsFrom 2,758 participants (44% men; mean age 61±9 years, range=29 to 86 years), five protein food clusters were identified (chicken, fish, processed foods, red meat, and low-fat milk). Three of these food clusters showed associations with BMD. The red meat protein food cluster presented with significantly lower femoral neck BMD compared with the low-fat milk cluster (red meat 0.898±0.005 g/cm(2) vs low-fat milk 0.919±0.007 g/cm(2); P=0.04). Further, the processed foods protein cluster presented with significantly lower femoral neck BMD compared with the low-fat milk cluster (processed foods 0.897±0.004 g/cm(2) vs low-fat milk 0.919±0.007 g/cm(2); P=0.02). A similar, yet nonsignificant, trend was observed for other BMD sites examined.
conclusionsDiets with the greatest proportion of protein intake from red meat and processed foods may not be as beneficial to the skeleton compared with dietary patterns where the highest proportion of protein is derived from low-fat milk.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.