ArticleJournal of psychiatric research2015
Childhood maltreatment, 9/11 exposure, and latent dimensions of psychopathology: A test of stress sensitization.
Article in Journal of psychiatric research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Adverse childhood experiences, exposure to the World Trade Center attacks, and chronic symptoms of depression, PTSD, and unhealthy drinking.Journal of affective disorders · 2026Article
- The effect of physical activity and life events on mental health of college students: the mediating role of psychological vulnerability.BMC psychology · 2025Article
- Trauma-Based Sexually Dimorphic Changes in the Connectome and Its Association with Central Sensitization Syndromes-A Systematic Review.Brain sciences · 2024Review
- COVID-19 pandemic stressors are associated with reported increases in frequency of drunkenness among individuals with a history of alcohol use disorder.Translational psychiatry · 2023Article
- Stressors and symptoms associated with a history of adverse childhood experiences among older adolescents and young adults during the COVID-19 pandemic in Manitoba, Canada.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2023Article
- Stress-related psychopathology during the COVID-19 pandemic.Behaviour research and therapy · 2022Review
- Using Danish national registry data to understand psychopathology following potentially traumatic experiences.Journal of traumatic stress · 2022Article
- Child Abuse in Times of Crises: Lessons Learned.Clinical pediatric emergency medicine · 2020Article
- Telepsychotherapy with Youth at Clinical High Risk for Psychosis: Clinical Issues and Best Practices during the COVID-19 Pandemic.Journal of psychotherapy integration · 2020Article
- Evidence that Different Types of Peer Victimization have Equivalent Associations with Transdiagnostic Psychopathology in Adolescence.Journal of youth and adolescence · 2020Observational
- Opportunities for the prevention of mental disorders by reducing general psychopathology in early childhood.Behaviour research and therapy · 2019Article
- A Hierarchical Taxonomy of Psychopathology Can Transform Mental Health Research.Perspectives on psychological science : a journal of the Association for Psychological Science · 2019Review
- DSM-5 cannabis withdrawal syndrome: Demographic and clinical correlates in U.S. adults.Drug and alcohol dependence · 2019Article
- Epigenetic Programming Effects of Early Life Stress: A Dual-Activation Hypothesis.Current genomics · 2018Review
- The Burden of Bereavement: Early-Onset Depression and Impairment in Youths Bereaved by Sudden Parental Death in a 7-Year Prospective Study.The American journal of psychiatry · 2018Article
- Mental disorder comorbidity and treatment utilization.Comprehensive psychiatry · 2017Article
- A 10-year prospective-longitudinal study of daily hassles and incident psychopathology among adolescents and young adults: interactions with gender, perceived coping efficacy, and negative life events.Social psychiatry and psychiatric epidemiology · 2017Article
- The Role of Trauma and Stressful Life Events among Individuals at Clinical High Risk for Psychosis: A Review.Frontiers in psychiatry · 2017Review
- Beyond comorbidity: Toward a dimensional and hierarchical approach to understanding psychopathology across the life span.Development and psychopathology · 2016Article
- Relations between childhood psychological maltreatment and mental health dimensions within a higher-order model.International journal of clinical and health psychology : IJCHPArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
On September 11, 2001, a terrorist attack occurred in the U.S. (9/11). Research on 9/11 and psychiatric outcomes has focused on individual disorders rather than the broader internalizing (INT) and externalizing (EXT) domains of psychopathology, leaving unknown whether direct and indirect 9/11 exposure differentially impacted these domains rather than individual disorders. Further, whether such effects were exacerbated by earlier childhood maltreatment (i.e. stress sensitization) is unknown. 18,713 participants from a U.S. national sample with no history of psychiatric disorders prior to 9/11 were assessed using a structured in-person interview. Structural equation modeling conducted in a sample who endorsed no psychiatric history prior to 9/11, indicated that indirect exposure to 9/11 (i.e. media, friends/family) was related to both EXT (alcohol, nicotine, and cannabis dependence, and antisocial personality disorder) and INT (major depression, generalized anxiety, and post-traumatic stress disorder (PTSD)) dimensions of psychopathology (EXT: β = 0.10, p < 0.001; INT: β = 0.11, p < 0.001) whereas direct exposure was associated with the INT dimension only (β = 0.11, p < 0.001). For individuals who had experienced childhood maltreatment, the risk for EXT and INT dimensions associated with 9/11 was exacerbated (Interactions: β = 0.06, p < 0.01; β = 0.07, p < 0.001, respectively). These findings indicate that 9/11 impacted latent liability to broad domains of psychopathology in the US general population rather than specific disorders with the exception of PTSD, which had independent effects beyond INT (as indicated by a significant (p < 0.05) improvement in modification indices). Findings also indicated that childhood maltreatment increases the risk associated with adult trauma exposure, providing further evidence for the concept of stress sensitization.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.