Evidence map›Paper›PMID 26037857›Full record

ArticleThe Journal of neuropsychiatry and clinical neurosciences2014

Diagnostic Utility of the International HIV Dementia Scale for HIV-Associated Neurocognitive Impairment and Disorder in South Africa.

Karl Goodkin, David J Hardy, Dinesh Singh, Enrique Lopez

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of neuropsychiatry and clinical neurosciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. HIV-Associated Neurocognitive Disorder (HAND): Relative Risk Factors.Current topics in behavioral neurosciences · 2021
    Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Interaction Effects between HIV and Aging on Selective Neurocognitive Impairment.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2017
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Karl GoodkinFrom the Dept. of Mental Health, AIDS Healthcare Foundation, Los Angeles, CA (KG); Dept. of Psychiatry and Behavioral Sciences, Quillen College of Medicine, East Tennessee State University, Johnson City, TN (KG); Dept. of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA (EL, DJH); Dept. of Psychology, Loyola Marymount University, Los Angeles, CA (DJH); Dept. of Psychiatry, McCord Hospital, Durban, South Africa (DS); and Dept. of Psychiatry and Behavioral Neurosciences, Cedars-Sinai Medical Center, Los Angeles, CA (EL).
David J HardyFrom the Dept. of Mental Health, AIDS Healthcare Foundation, Los Angeles, CA (KG); Dept. of Psychiatry and Behavioral Sciences, Quillen College of Medicine, East Tennessee State University, Johnson City, TN (KG); Dept. of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA (EL, DJH); Dept. of Psychology, Loyola Marymount University, Los Angeles, CA (DJH); Dept. of Psychiatry, McCord Hospital, Durban, South Africa (DS); and Dept. of Psychiatry and Behavioral Neurosciences, Cedars-Sinai Medical Center, Los Angeles, CA (EL).
Dinesh SinghFrom the Dept. of Mental Health, AIDS Healthcare Foundation, Los Angeles, CA (KG); Dept. of Psychiatry and Behavioral Sciences, Quillen College of Medicine, East Tennessee State University, Johnson City, TN (KG); Dept. of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA (EL, DJH); Dept. of Psychology, Loyola Marymount University, Los Angeles, CA (DJH); Dept. of Psychiatry, McCord Hospital, Durban, South Africa (DS); and Dept. of Psychiatry and Behavioral Neurosciences, Cedars-Sinai Medical Center, Los Angeles, CA (EL).
Enrique LopezFrom the Dept. of Mental Health, AIDS Healthcare Foundation, Los Angeles, CA (KG); Dept. of Psychiatry and Behavioral Sciences, Quillen College of Medicine, East Tennessee State University, Johnson City, TN (KG); Dept. of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA (EL, DJH); Dept. of Psychology, Loyola Marymount University, Los Angeles, CA (DJH); Dept. of Psychiatry, McCord Hospital, Durban, South Africa (DS); and Dept. of Psychiatry and Behavioral Neurosciences, Cedars-Sinai Medical Center, Los Angeles, CA (EL).

Funding

TUBERCULOSIS SUPPLEMENTD43TW000231 · FIC · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI ABDOOL KARIM, QUARRAISHA · 1993 to 2014
$13.1M
FIC NIH HHS 5-D43-TW00231FIC NIH HHS D43 TW000231
6 · The paper itself

Abstract

Studies in sub-Saharan Africa indicate that most HIV seropositive persons have HIV-associated neurocognitive disorder (HAND). HAND diagnosis is facilitated by specific screening. Seventy participants were recruited from an HIV voluntary counseling and testing clinic in Durban, South Africa. The diagnostic utility of the International HIV Dementia Scale (IHDS) was analyzed using a receiver operating characteristic (ROC) model. The ROC analysis comparing any HAND diagnosis (based on two neuropsychological tests) versus no diagnosis was statistically significant, with an optimal cut-off score of 10.5, sensitivity of 69%, and specificity of 74%. Sensitivity of the IHDS was highest for HIV-associated dementia.

Indexed as

Neuropsychological TestsAdultAIDS Dementia ComplexCD4 AntigensFemaleHumansMaleReproducibility of ResultsROC CurveSouth AfricaYoung AdultCD4 Antigens

Identifiers

PMID26037857
PMCPMC5805556

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.