Evidence map›Paper›PMID 26037718›Full record

ArticleEuropean radiology2016

Optimizing radiation dose by using advanced modelled iterative reconstruction in high-pitch coronary CT angiography.

Sonja Gordic, Lotus Desbiolles, Martin Sedlmair, Robert Manka, André Plass, Bernhard Schmidt, Daniela B Husarik, Francesco Maisano, Simon Wildermuth, Hatem Alkadhi and 1 more

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Article in European radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 49 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Sonja GordicInstitute of Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Raemistrasse 100, CH-8091, Zurich, Switzerland.
Lotus DesbiollesInstitute of Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Raemistrasse 100, CH-8091, Zurich, Switzerland.
Martin SedlmairSiemens Healthcare, Computed Tomography Division, Forchheim, Germany.
Robert MankaInstitute of Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Raemistrasse 100, CH-8091, Zurich, Switzerland.
André PlassClinic for Cardiovascular Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Bernhard SchmidtSiemens Healthcare, Computed Tomography Division, Forchheim, Germany.
Daniela B HusarikInstitute of Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Raemistrasse 100, CH-8091, Zurich, Switzerland.
Francesco MaisanoClinic for Cardiovascular Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Simon WildermuthDivison of Radiology and Nuclear Medicine, Kantonsspital, St. Gallen, Switzerland.
Hatem AlkadhiInstitute of Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Raemistrasse 100, CH-8091, Zurich, Switzerland. hatem.alkadhi@usz.ch.
Sebastian LeschkaInstitute of Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Raemistrasse 100, CH-8091, Zurich, Switzerland.
University Hospital of Zurich · CHUniversity of Zurich · CHKantonsspital St. Gallen · CHSiemens Healthcare (Germany) · DEInstitute for Biomedical Engineering · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the potential of advanced modeled iterative reconstruction (ADMIRE) for optimizing radiation dose of high-pitch coronary CT angiography (CCTA).

methodsHigh-pitch 192-slice dual-source CCTA was performed in 25 patients (group 1) according to standard settings (ref. 100 kVp, ref. 270 mAs/rot). Images were reconstructed with filtered back projection (FBP) and ADMIRE (strength levels 1-5). In another 25 patients (group 2), high-pitch CCTA protocol parameters were adapted according to results from group 1 (ref. 160 mAs/rot), and images were reconstructed with ADMIRE level 4. In ten patients of group 1, vessel sharpness using full width at half maximum (FWHM) analysis was determined. Image quality was assessed by two independent, blinded readers.

resultsInterobserver agreements for attenuation and noise were excellent (r = 0.88/0.85, p < 0.01). In group 1, ADMIRE level 4 images were most often selected (84%, 21/25) as preferred data set; at this level noise reduction was 40% compared to FBP. Vessel borders showed increasing sharpness (FWHM) at increasing ADMIRE levels (p < 0.05). Image quality in group 2 was similar to that of group 1 at ADMIRE levels 2-3. Radiation dose in group 2 (0.3 ± 0.1 mSv) was significantly lower than in group 1 (0.5 ± 0.3 mSv; p < 0.05).

conclusionsIn a selected population, ADMIRE can be used for optimizing high-pitch CCTA to an effective dose of 0.3 mSv. KEY POINTS: • Advanced modeled IR (ADMIRE) reduces image noise up to 50% as compared to FBP. • Coronary artery vessel borders show an increasing sharpness at higher ADMIRE levels. • High-pitch CCTA with ADMIRE is possible at a radiation dose of 0.3 mSv.

Indexed as

Radiation DosageAdultAgedAged, 80 and overCoronary AngiographyFemaleHumansImage Processing, Computer-AssistedMaleMiddle AgedRadiographic Image EnhancementRadiographic Image Interpretation, Computer-AssistedRetrospective StudiesTomography, X-Ray ComputedComputed tomographyCoronary angiographyImage qualityIterative reconstructionRadiation dose

Identifiers

PMID26037718
OpenAlexW566185079

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.