ArticleApplied spectroscopy2015
Goldindec: A Novel Algorithm for Raman Spectrum Baseline Correction.
Article in Applied spectroscopy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Article
- Beyond Traditional airPLS: Improved Baseline Removal in SERS with Parameter-Focused Optimization and Prediction.Analytical chemistry · 2025Article
- Article
- Artifacts and Anomalies in Raman Spectroscopy: A Review on Origins and Correction Procedures.Molecules (Basel, Switzerland) · 2024Review
- Classification of osteoarthritic and healthy cartilage using deep learning with Raman spectra.Scientific reports · 2024Article
- Towards routine organic structure determination using Raman microscopy.Chemical science · 2024Article
- Alterations in the molecular composition of COVID-19 patient urine, detected using Raman spectroscopic/computational analysis.PloS one · 2022Article
- An Automatic Baseline Correction Method Based on the Penalized Least Squares Method.Sensors (Basel, Switzerland) · 2020Article
- A Statistical Approach of Background Removal and Spectrum Identification for SERS Data.Scientific reports · 2020Article
- Article
- Spectral characteristics of urine from patients with end-stage kidney disease analyzed using Raman Chemometric Urinalysis (Rametrix).PloS one · 2020Article
- The RametrixPeerJ · 2020Article
- Article
- Article
- Multivariate Analysis of Difference Raman Spectra of the Irradiated Nucleus and Cytoplasm Region of SH-SY5Y Human Neuroblastoma Cells.Sensors (Basel, Switzerland) · 2019Article
- Spectral characteristics of urine specimens from healthy human volunteers analyzed using Raman chemometric urinalysis (Rametrix).PloS one · 2019Article
- Collaborative Penalized Least Squares for Background Correction of Multiple Raman Spectra.Journal of analytical methods in chemistry · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Raman spectra have been widely used in biology, physics, and chemistry and have become an essential tool for the studies of macromolecules. Nevertheless, the raw Raman signal is often obscured by a broad background curve (or baseline) due to the intrinsic fluorescence of the organic molecules, which leads to unpredictable negative effects in quantitative analysis of Raman spectra. Therefore, it is essential to correct this baseline before analyzing raw Raman spectra. Polynomial fitting has proven to be the most convenient and simplest method and has high accuracy. In polynomial fitting, the cost function used and its parameters are crucial. This article proposes a novel iterative algorithm named Goldindec, freely available for noncommercial use as noted in text, with a new cost function that not only conquers the influence of great peaks but also solves the problem of low correction accuracy when there is a high peak number. Goldindec automatically generates parameters from the raw data rather than by empirical choice, as in previous methods. Comparisons with other algorithms on the benchmark data show that Goldindec has a higher accuracy and computational efficiency, and is hardly affected by great peaks, peak number, and wavenumber.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.