Evidence map›Paper›PMID 26037603›Full record

ArticleAnnals of the New York Academy of Sciences2015

Early-life influences on obesity: from preconception to adolescence.

Mark L Wahlqvist, Stephen A Krawetz, Nico S Rizzo, Maria Gloria Dominguez-Bello, Linda M Szymanski, Shari Barkin, Ann Yatkine, Robert A Waterland, Julie A Mennella, Mina Desai and 6 more

Abstract readConference Proceedings
In one paragraph

Article in Annals of the New York Academy of Sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Obesogens: a unifying theory for the global rise in obesity.International journal of obesity (2005) · 2024
    Review
  10. Shaping Microbiota During the First 1000 Days of Life.Advances in experimental medicine and biology · 2024
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Obesity: global epidemiology and pathogenesis.Nature reviews. Endocrinology · 2019
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Mark L WahlqvistZhejiang University, Hangzhou, China.
Stephen A KrawetzC.S. Mott Center for Human Growth and Development and Center for Molecular Medicine and Genetics, Department of Obstetrics and Gynecology, Wayne State University, Detroit, Michigan.
Nico S RizzoCenter of Community Resilience, School of Public Health, Loma Linda University, Loma Linda, California.
Maria Gloria Dominguez-BelloNew York University School of Medicine, New York, New York.
Linda M SzymanskiJohns Hopkins University School of Medicine, Baltimore, Maryland.
Shari BarkinVanderbilt University Medical Center, Nashville, Tennessee.
Ann YatkineVanderbilt University Medical Center, Nashville, Tennessee.
Robert A WaterlandDepartments of Pediatrics and Molecular and Human Genetics, Baylor College of Medicine and USDA/ARS Children's Nutrition Research Center, Houston, Texas.
Julie A MennellaMonell Chemical Senses Center, Philadelphia, Pennsylvania.
Mina DesaiUniversity of California Los Angeles Medical Center, Los Angeles, California.
Michael G RossUniversity of California Los Angeles Medical Center, Los Angeles, California.
Nancy F KrebsUniversity of Colorado School of Medicine, Aurora, Colorado.
Bridget E YoungUniversity of Colorado School of Medicine, Aurora, Colorado.
Jane WardleDepartment of Epidemiology and Public Health, University College London, London, United Kingdom.
Christiane D WrannDana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, Massachusetts.
John G KralSUNY Downstate Medical Center, Brooklyn, New York.

Funding

CONTROL OF ADIPOCYTE GENE EXPRESSION AND PHYSIOLOGYR37DK031405 · NIDDK · DANA-FARBER CANCER INSTITUTE · PI SPIEGELMAN, BRUCE M. · 1996 to 2013
$8.2M
Taste of medicines for children: genetic variation and medical adherenceR01DC011287 · NIDCD · MONELL CHEMICAL SENSES CENTER · PI LOWENTHAL, ELIZABETH DAWN, MENNELLA, JULIA ANNE · 2011 to 2022
$4.3M
Regulation of Brown Fat: Toward New Therapy for Human ObesityRC4DK090861 · NIDDK · DANA-FARBER CANCER INST · PI SPIEGELMAN, BRUCE M. · 2010 to 2010
$4.2M
MODEL FOR SENSITIVE PERIODS IN EARLY FLAVOR LEARNINGR01HD037119 · NICHD · MONELL CHEMICAL SENSES CENTER · PI MENNELLA, JULIA ANNE · 1999 to 2016
$3.9M
CONTROL OF LIPOGENIC ENZYME SYNTHESIS IN ADIPOCYTESR01DK031405 · NIDDK · DANA-FARBER CANCER INSTITUTE · PI SPIEGELMAN, BRUCE M. · 1986 to 2018
$2.9M
Impact of diet composition during infancy on energy balance, satiety and growthR01HD072307 · NICHD · MONELL CHEMICAL SENSES CENTER · PI MENNELLA, JULIA ANNE, TRABULSI, JILLIAN CHRISTINE · 2012 to 2016
$2.7M
Molecular mechanisms of exercise benefits in synapse plasticity and cognitionR00NS087096 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI WRANN, CHRISTIANE D. · 2017 to 2019
$745k
Molecular mechanisms of exercise benefits in synapse plasticity and cognitionK99NS087096 · NINDS · DANA-FARBER CANCER INST · PI WRANN, CHRISTIANE D. · 2014 to 2015
$223k
SECONDARY ANALYSES OF RCT DATA ON SENSITIVE PERIODS IN FLAVOR LEARNING AND DIET AMONG BREASTFEEDING DYADSR03HD102303 · NICHD · MONELL CHEMICAL SENSES CENTER · PI MENNELLA, JULIA ANNE, TRABULSI, JILLIAN CHRISTINE · 2020 to 2021
$196k
Cancer Research UK 14133NICHD NIH HHS HD072307NICHD NIH HHS HD37119NICHD NIH HHS R01 HD037119NICHD NIH HHS R01 HD072307NICHD NIH HHS R03 HD102303NIDCD NIH HHS DC011287NIDCD NIH HHS R01 DC011287NIDDK NIH HHS DK31405NIDDK NIH HHS DK90861NIDDK NIH HHS R01 DK031405NIDDK NIH HHS R37 DK031405NIDDK NIH HHS RC4 DK090861NINDS NIH HHS K99 NS087096NINDS NIH HHS NS087096NINDS NIH HHS R00 NS087096
6 · The paper itself

Abstract

The double burden of under- and overnutrition profoundly affects human health globally. According to the World Health Organization, obesity and diabetes rates have almost doubled worldwide since 1980, and, in 2011, more than 40 million children under 5 years of age were overweight. Ecologic factors, parental genetics and fitness, and the intrauterine environment significantly influence the likelihood of offspring developing the dysmetabolic diathesis of obesity. This report examines the effects of these factors, including preconception, intrauterine and postnatal energy balance affecting programming of transgenerational transmission, and development of chronic diseases later in life-in particular, diabesity and its comorbidities.

Indexed as

Feeding BehaviorFood PreferencesAdolescentBreast FeedingChildDiabetes MellitusEnergy MetabolismExerciseHealth BehaviorHumansLife StyleObesityOvernutritionbreast feedingdiabesityeconutritionalepigeneticsexercisemicrobiomenutritionobesitytaste preferences

Identifiers

PMID26037603
PMCPMC4522218

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.