ArticleJournal of autism and developmental disorders2015
The association between autism spectrum disorders and congenital anomalies by organ systems in a Finnish national birth cohort.
Article in Journal of autism and developmental disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- Neurodevelopmental outcomes in individuals with VACTERL association. A population-based cohort study.PloS one · 2023Article
- Scribble Controls Social Motivation Behavior through the Regulation of the ERK/Mnk1 Pathway.Cells · 2022Article
- Autism spectrum disorder and kidney disease.Pediatric nephrology (Berlin, Germany) · 2021Review
- Suckling, Feeding, and Swallowing: Behaviors, Circuits, and Targets for Neurodevelopmental Pathology.Annual review of neuroscience · 2020Review
- The Association Between Somatic Health, Autism Spectrum Disorder, and Autistic Traits.Behavior genetics · 2020Article
- Mercury-associated diagnoses among children diagnosed with pervasive development disorders.Metabolic brain disease · 2018Article
- Prevalence and Correlates of Autism Spectrum Disorders in Quebec: Prévalence et corrélats des troubles du spectre de l'autisme au Québec.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2018Article
- Invited Commentary: Male Reproductive System Congenital Malformations and the Risk of Autism Spectrum Disorder.American journal of epidemiology · 2018Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 3 countries.
Funding
Abstract
The aim of this study was to evaluate the association between autism spectrum disorders (ASD) with and without intellectual disability (ID) and congenital anomalies (CAs) by organ system. The sample included all children diagnosed with ASD (n = 4441) from the Finnish Hospital Discharge Register during 1987-2000 and a total of four controls per case (n = 17,695). CAs of the eye, central nervous system, and specific craniofacial anomalies were most strongly associated with ASD. Children with ASD and co-occurring ID were more likely to have CAs compared to ASD children without ID. The results suggest that some cases of ASD may originate during organogenesis, in the early first trimester of pregnancy. The results of this study may be useful for identifying prenatal etiological factors and elucidating the molecular pathogenesis of ASD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.