ReviewInternational journal of molecular sciences2015
Ecotoxicogenomic approaches for understanding molecular mechanisms of environmental chemical toxicity using aquatic invertebrate, Daphnia model organism.
Review in International journal of molecular sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed.
- Advances in ecotoxicological research using planarians: a comprehensive review.Environmental science and pollution research international · 2026Review
- Article
- A web-based histology atlas for the freshwater sentinel species Daphnia magna.The Science of the total environment · 2025Article
- History of exposure to copper influences transgenerational gene expression responses inEpigenetics · 2024Article
- Exploring the Sublethal Impacts of Cu and Zn on Daphnia magna: a transcriptomic perspective.BMC genomics · 2024Article
- Emerging contaminants: A One Health perspective.Innovation (Cambridge (Mass.)) · 2024Review
- Five years after the collapse of the Fundão Dam: lessons from temporal monitoring of chemistry and acute toxicity.Environmental monitoring and assessment · 2024Article
- Daphnia magna as a Model Organism to Predict the Teratogenic Effect of Different Compounds.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Cheminformatics and Machine Learning Approaches to Assess Aquatic Toxicity Profiles of Fullerene Derivatives.International journal of molecular sciences · 2023Article
- Article
- The impact of selected abiotic factors on Artemia hatching process through real-time observation of oxygen changes in a microfluidic platform.Scientific reports · 2023Article
- Polystyrene nanoplastics differentially influence the outcome of infection by two microparasites of the hostPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
- Polyacrylamide Hydrogel Enriched with Amber for In Vitro Plant Rooting.Plants (Basel, Switzerland) · 2023Article
- In silico analysis decodes transthyretin (TTR) binding and thyroid disrupting effects of per- and polyfluoroalkyl substances (PFAS).Archives of toxicology · 2023Article
- Influence of water hardness on zinc toxicity in Daphnia magna.Journal of applied toxicology : JAT · 2022Article
- Transcriptomic Alterations in Water Flea (Toxics · 2022Article
- Persistent pesticides: effects of endosulfan at the molecular level on the aquatic invertebrate Chironomus riparius.Environmental science and pollution research international · 2021Article
- Single-Larva RNA Sequencing Identifies Markers of Copper Toxicity and Exposure in EarlyFrontiers in physiology · 2021Article
- Alternative splicing is highly variable among Daphnia pulex lineages in response to acute copper exposure.BMC genomics · 2020Article
- Molecular Nanomachines Can Destroy Tissue or Kill Multicellular Eukaryotes.ACS applied materials & interfaces · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Due to the rapid advent in genomics technologies and attention to ecological risk assessment, the term "ecotoxicogenomics" has recently emerged to describe integration of omics studies (i.e., transcriptomics, proteomics, metabolomics, and epigenomics) into ecotoxicological fields. Ecotoxicogenomics is defined as study of an entire set of genes or proteins expression in ecological organisms to provide insight on environmental toxicity, offering benefit in ecological risk assessment. Indeed, Daphnia is a model species to study aquatic environmental toxicity designated in the Organization for Economic Co-operation and Development's toxicity test guideline and to investigate expression patterns using ecotoxicology-oriented genomics tools. Our main purpose is to demonstrate the potential utility of gene expression profiling in ecotoxicology by identifying novel biomarkers and relevant modes of toxicity in Daphnia magna. These approaches enable us to address adverse phenotypic outcomes linked to particular gene function(s) and mechanistic understanding of aquatic ecotoxicology as well as exploration of useful biomarkers. Furthermore, key challenges that currently face aquatic ecotoxicology (e.g., predicting toxicant responses among a broad spectrum of phytogenetic groups, predicting impact of temporal exposure on toxicant responses) necessitate the parallel use of other model organisms, both aquatic and terrestrial. By investigating gene expression profiling in an environmentally important organism, this provides viable support for the utility of ecotoxicogenomics.
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Registered trials
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