ArticleMarine drugs2015
New Anti-Inflammatory Cembranes from the Cultured Soft Coral Nephthea columnaris.
Article in Marine drugs, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Cembranoids from the cultured soft coralRSC advances · 2026Article
- UPLC-qToF-MS/MS analysis and anti-inflammatory activities of the soft coralRSC advances · 2026Article
- New Meroterpenes from South China Sea Soft CoralMarine drugs · 2024Article
- GenusMarine drugs · 2023Review
- The application and sustainable development of coral in traditional medicine and its chemical composition, pharmacology, toxicology, and clinical research.Frontiers in pharmacology · 2023Review
- Towards Sustainable Medicinal Resources through Marine Soft Coral Aquaculture: Insights into the Chemical Diversity and the Biological Potential.Marine drugs · 2022Review
- Research Progress in Anti-Inflammatory Bioactive Substances Derived from Marine Microorganisms, Sponges, Algae, and Corals.Marine drugs · 2021Review
- Chemical and biological studies on the soft coralRSC advances · 2021Article
- Coral and Coral-Associated Microorganisms: A Prolific Source of Potential Bioactive Natural Products.Marine drugs · 2019Review
- Review
- Screening of NO Inhibitor Release Activity from Soft Coral Extracts Origin Palu Bay, Central Sulawesi, Indonesia.Anti-inflammatory & anti-allergy agents in medicinal chemistry · 2019Article
- The Holo-Transcriptome of the ZoantharianMarine drugs · 2018Article
- Aquaculture Soft Coral Lobophytum crassum as a Producer of Anti-Proliferative Cembranoids.Marine drugs · 2018Article
- Anti-Inflammatory Dembranoids from the Soft Coral Lobophytum crassum.Marine drugs · 2017Article
- Immuno-Modulatory and Anti-Inflammatory Effects of Dihydrogracilin A, a Terpene Derived from the Marine Sponge Dendrilla membranosa.International journal of molecular sciences · 2017Article
- Sterols from the Octocoral Nephthea columnaris.Marine drugs · 2017Article
- Isoprenoids from the Soft Coral Sarcophyton glaucum.Marine drugs · 2017Article
- New cembranoid diterpenes from the cultured octocoral Nephthea columnaris.Molecules (Basel, Switzerland) · 2015Article
- Marine Diterpenoids as Potential Anti-Inflammatory Agents.Mediators of inflammation · 2015Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two new cembranes, columnariols A (1) and B (2), were isolated from the cultured soft coral Nephthea columnaris. The structures of cembranes 1 and 2 were elucidated by spectroscopic methods. In the anti-inflammatory effects test, cembranes 1 and 2 were found to significantly inhibit the accumulation of the pro-inflammatory iNOS and COX-2 protein of the lipopolysaccharide (LPS)-stimulated RAW264.7 macrophage cells. Compound 1 exhibited moderate cytotoxicity toward LNCaP cells with an IC50 value of 9.80 μg/mL.
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Registered trials
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