ArticleMedicina oral, patologia oral y cirugia bucal2015
Repair of bone defect by nano-modified white mineral trioxide aggregates in rabbit: A histopathological study.
Article in Medicina oral, patologia oral y cirugia bucal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Physicochemical, mechanical and biological properties of nano-calcium silicate-based cements: a systematic review.Odontology · 2023Pooled it
- Remineralization ability of different root canal sealers.The Saudi dental journal · 2023Article
- The Effect of a Setting Accelerator on the Physical and Mechanical Properties of a Fast-set White Portland Cement Mixed with Nano-zirconium Oxide.European endodontic journal · 2023Article
- Morphological Characteristics of the Osteoplastic Potential of Synthetic CaSiOJournal of functional biomaterials · 2020Article
- Nanotechnology Scaffolds for Alveolar Bone Regeneration.Materials (Basel, Switzerland) · 2020Review
- Cytotoxicity of Selected Nanoparticles on Human Dental Pulp Stem Cells.Iranian endodontic journal · 2017Article
- The role of angiogenesis in implant dentistry part II: The effect of bone-grafting and barrier membrane materials on angiogenesis.Medicina oral, patologia oral y cirugia bucal · 2016Review
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7 authors.
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Abstract
backgroundMany researchers have tried to enhance materials functions in different aspects of science using nano-modification method, and in many cases the results have been encouraging. To evaluate the histopathological responses of the micro-/nano-size cement-type biomaterials derived from calcium silicate-based composition with addition of nano tricalcium aluminate (3CaO.Al2O3) on bone healing response. MATERIAL AND
methodsNinety mature male rabbits were anesthetized and a bone defect was created in the right mandible. The rabbits were divided into three groups, which were in turn subdivided into five subgroups with six animals each based on the defect filled by: white mineral trioxide aggregate (WMTA), Nano-WMTA, WMTA without 3CaO.Al2O3, Nano-WMTA with 2% Nano-3CaO.Al2O3, and empty as control. Twenty, forty and sixty days postoperatively the animals were sacrificed and the right mandibles were removed for histopathological evaluations. Kruskal-Wallis test with post-hoc comparisons based on the LSMeans procedure was used for data analysis.
resultsAll the experimental materials provoked a moderate to severe inflammatory reaction, which significantly differed from the control group (p< 0.05). Statistical analysis of bone formation and bone regeneration data showed significant differences between groups at 40- and 60- day intervals in all groups. Absence of 3CaO.Al2O3 leads to more inflammation and foreign body reaction than other groups in all time intervals.
conclusionsBoth powder nano-modification and addition of 2% Nano-3CaO.Al2O3 to calcium silicate-based cement enhanced the favorable tissue response and osteogenesis properties of WMTA based materials.
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