ArticleMedical journal of the Islamic Republic of Iran2015
The effect of exercise therapy on knee osteoarthritis: a randomized clinical trial.
Article in Medical journal of the Islamic Republic of Iran, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 21 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Evidence Regarding The Dynamic of Baker Cyst Dimensions After Intermittent Vacuum Therapy As Rehabilitation Treatment In Patients With Knee Osteoarthritis
Effect of mechanical traction applied before versus after therapeutic exercises on clinical and functional outcomes in primary knee osteoarthritis
Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Exercise for osteoarthritis of the knee.The Cochrane database of systematic reviews · 2024Pooled it
- Is high intensity laser therapy more effective than other physical therapy modalities for treating knee osteoarthritis? A systematic review and network meta-analysis.Frontiers in medicine · 2022Pooled it
- A recommended exercise program appropriate for patients with knee osteoarthritis: A systematic review and meta-analysis.Frontiers in physiology · 2022Pooled it
- Osteoarthritis- a systematic review of long-term safety implications for osteoarthritis of the knee.BMC musculoskeletal disorders · 2019Pooled it
- Effects of a two-week instrument-assisted soft tissue mobilization and exercise therapy versus sham and exercise on gait kinetics in moderate knee osteoarthritis: a randomized controlled trial.The Journal of manual & manipulative therapy · 2026Trial
- Effects of instrument-assisted soft tissue mobilization combined with exercise on knee joint muscle activity during walking in patients with moderate knee osteoarthritis: A randomized controlled clinical trial.Scientific reports · 2025Trial
- Comparison of the effects of high-intensity laser therapy and low-level laser therapy in knee osteoarthritis.Clinical rheumatology · 2025Trial
- Efficacy of high-intensity laser therapy in comparison with conventional physiotherapy and exercise therapy on pain and function of patients with knee osteoarthritis: a randomized controlled trial with 12-week follow up.Lasers in medical science · 2019Trial
- Effectiveness of therapeutic exercise and platelet-rich plasma in the case of knee osteoarthritis.Journal of physical therapy science · 2025Article
- Deep Front Line Myofascial Release Versus Novel Soft Tissue Kinetic Chain Activation Technique (K-CAT) on Pain, Radiological Patellar Position and Dynamic Knee Valgus in Knee Osteoarthritis: A Randomized Clinical Trial.International journal of therapeutic massage & bodywork · 2025Article
- Aerobic and Resistance Training Attenuate Differently Knee Joint Damage Caused by a High-Fat-High-Sucrose Diet in a Rat Model.Cartilage · 2024Article
- A novelOsteoarthritis and cartilage open · 2024Article
- Clinical Evidence Regarding the Dynamic of Baker Cyst Dimensions after Intermittent Vacuum Therapy as Rehabilitation Treatment in Patients with Knee Osteoarthritis.Journal of clinical medicine · 2023Article
- Association of physical activity with physical function and quality of life in people with hip and knee osteoarthritis: longitudinal analysis of a population-based cohort.Arthritis research & therapy · 2023Article
- Effect of aqua walking exercise on knee joint angles, muscular strength, and visual analogue scale for patients with limited range of motion of the knee.Journal of exercise rehabilitation · 2021Article
- Advantages and challenges of stem cell therapy for osteoarthritis (Review).Biomedical reports · 2021Review
- Functionality in Middle-Aged and Older Overweight and Obese Individuals with Knee Osteoarthritis.Healthcare (Basel, Switzerland) · 2018Article
- Osteoarthritis and the Complement Cascade.Clinical medicine insights. Arthritis and musculoskeletal disorders · 2018Review
- Expression and Significance of High-Mobility Group Protein B1 (HMGB1) and the Receptor for Advanced Glycation End-Product (RAGE) in Knee Osteoarthritis.Medical science monitor : international medical journal of experimental and clinical research · 2016Article
- Comparative Impact of Nonpharmacological Interventions on Pain of Knee Osteoarthritis Patients Reporting at a Tertiary Care Institution: A Randomized Controlled Trial.Indian journal of palliative careArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundKnee osteoarthritis (OA) is the most common musculoskeletal disease among old individuals which affects ability for sitting on the chair, standing, walking and climbing stairs. Our objective was to investigate the short and long-term effects of the most simple and the least expensive exercise protocols in combination to conventional conservative therapy for knee OA.
methodsIt was a single blind RCT study with a 12-months follow-up. Totally, 56 patients with knee OA were assigned into 2 random groups. The patients in exercise group received exercise for knee muscles in combination with non-steroid anti-inflammatory drugs (NSAIDs) and 10 sessions acupuncture and physiotherapy modalities. Non-exercise group received similar treatments except exercise program. The changes in patients' pain and functional status were evaluated by visual analog scale (VAS), knee and osteoarthritis outcome score (KOOS) questionnaire and functional tests (4 steps, 5 sit up, and 6 min walk test) before and after treatment (1 and 3 months after intervention), and 1 year later at the follow-up.
resultsThe results showed that the patients with knee OA in exercise group had significant improvement in pain, disability, walking, stair climbing, and sit up speed after treatment at first and second follow-up when compared with their initial status and when compared with non-exercise group. At third follow up (1 year later) there was significant difference between groups in VAS and in three items of KOOS questionnaire in functional status.
conclusionNon aerobic exercises for muscles around knee can augment the effect of other therapeutic interventions like medical therapy, acupuncture, and modalities for knee OA.
Indexed as
Identifiers
26034739PMC4431424W2165755267What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.