Evidence map›Paper›PMID 26034599›Full record

ArticleClinical kidney journal2015

Heroin crystal nephropathy.

Josef Edrik Keith Bautista, Basma Merhi, Oliver Gregory, Susie Hu, Kammi Henriksen, Reginald Gohh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical kidney journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Acute toxic kidney injury.Renal failure · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Josef Edrik Keith BautistaDivision of Kidney Disease and Hypertension, Department of Medicine , Rhode Island Hospital, Brown University School of Medicine , Providence, RI , USA.
Basma MerhiDivision of Kidney Disease and Hypertension, Department of Medicine , Rhode Island Hospital, Brown University School of Medicine , Providence, RI , USA.
Oliver GregoryDepartment of Medicine , Rhode Island Hospital, Brown University School of Medicine , Providence, RI , USA.
Susie HuDivision of Kidney Disease and Hypertension, Department of Medicine , Rhode Island Hospital, Brown University School of Medicine , Providence, RI , USA.
Kammi HenriksenDepartment of Pathology , University of Chicago Medical Center , Chicago, IL , USA.
Reginald GohhDivision of Kidney Disease and Hypertension, Department of Medicine , Rhode Island Hospital, Brown University School of Medicine , Providence, RI , USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper we present an interesting case of acute kidney injury and severe metabolic alkalosis in a patient with a history of heavy heroin abuse. Urine microscopy showed numerous broomstick-like crystals. These crystals are also identified in light and electron microscopy. We hypothesize that heroin crystalizes in an alkaline pH, resulting in tubular obstruction and acute kidney injury. Management is mainly supportive as there is no known specific therapy for this condition. This paper highlights the utility of urine microscopy in diagnosing the etiology of acute kidney injury and proposes a novel disease called heroin crystal nephropathy.

Indexed as

acute kidney injurycrystal nephropathyheroin nephropathyurinalysisurine microscopy

Identifiers

PMID26034599
PMCPMC4440465

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.