Evidence map›Paper›PMID 26034491›Full record

ArticleJournal of contemporary brachytherapy2015

A new two-step accurate CT-MRI fusion technique for post-implant prostate cancer.

Hiroaki Kunogi, Hidehiro Hojo, Yoshiaki Wakumoto, Anneyuko I Saito, Satoshi Ishikura, Yuki Yamashiro, Ryouhei Kuwatsuru, Keisuke Sasai

Open access · goldAbstract read
In one paragraph

Article in Journal of contemporary brachytherapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Hiroaki KunogiDepartment of Radiation Oncology, Juntendo University, Tokyo, Japan.
Hidehiro HojoDepartment of Radiation Oncology, Juntendo University, Tokyo, Japan.
Yoshiaki WakumotoDepartment of Urology, Juntendo University, Tokyo, Japan.
Anneyuko I SaitoDepartment of Radiation Oncology, Juntendo University, Tokyo, Japan.
Satoshi IshikuraDepartment of Radiation Oncology, Juntendo University, Tokyo, Japan.
Yuki YamashiroDepartment of Radiology, Juntendo University, Tokyo, Japan.
Ryouhei KuwatsuruDepartment of Radiology, Juntendo University, Tokyo, Japan.
Keisuke SasaiDepartment of Radiation Oncology, Juntendo University, Tokyo, Japan.
Juntendo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo develop an accurate method of fusing computed tomography (CT) with magnetic resonance imaging (MRI) for post-implant dosimetry after prostate seed implant brachytherapy. MATERIAL AND

methodsProstate cancer patients were scheduled to undergo CT and MRI after brachytherapy. We obtained the three MRI sequences on fat-suppressed T1-weighted imaging (FST1-WI), T2-weighted imaging (T2-WI), and T2*-weighted imaging (T2*-WI) in each patient. We compared the lengths and widths of 450 seed source images in the 10 study patients on CT, FST1-WI, T2-WI, and T2*-WI. After CT-MRI fusion using source positions by the least-squares method, we decided the center of each seed source and measured the distance of these centers between CT and MRI to estimate the fusion accuracy.

resultsThe measured length and width of the seeds were 6.1 ± 0.5 mm (mean ± standard deviation) and 3.2 ± 0.2 mm on CT, 5.9 ± 0.4 mm, and 2.4 ± 0.2 mm on FST1-WI, 5.5 ± 0.5 mm and 1.8 ± 0.2 mm on T2-WI, and 7.8 ± 1.0 mm and 4.1 ± 0.7 mm on T2*-WI, respectively. The measured source location shifts on CT/FST1-WI and CT/T2-WI after image fusion in the 10 study patients were 0.9 ± 0.4 mm and 1.4 ± 0.2 mm, respectively. The shift on CT/FST1-WI was less than on CT/T2-WI (p = 0.005).

conclusionsFor post-implant dosimetry after prostate seed implant brachytherapy, more accurate fusion of CT and T2-WI is achieved if CT and FST1-WI are fused first using the least-squares method and the center position of each source, followed by fusion of the FST1-WI and T2-WI images. This method is more accurate than direct image fusion.

Indexed as

brachytherapyfusionmagnetic resonance imagingpost-implantprostate cancer

Identifiers

PMID26034491
PMCPMC4444459
OpenAlexW2398945408

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.