Evidence map›Paper›PMID 26034341›Full record

ArticleCeramics international2015

Biologic Potential of Calcium Phosphate Biopowders Produced via Decomposition Combustion Synthesis.

N Vollmer, K B King, R Ayers

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ceramics international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

N VollmerGeorge S. Ansell Department of Metallurgy and Materials Engineering, Colorado School of Mines, 1500 Illinois Street, Golden, Colorado, 80401, USA.
K B KingUniversity of Colorado School of Medicine, Department of Orthopaedics, Aurora, Colorado, 80045, USA.
R AyersUniversity of Colorado School of Medicine, Department of Orthopaedics, Aurora, Colorado, 80045, USA.

Funding

The Anelastic Strain Response of Spine Rods in a Biologic EnvironmentR15AR060011 · NIAMS · COLORADO SCHOOL OF MINES · PI AYERS, REED A · 2010 to 2010
$287k
NIAMS NIH HHS R15 AR060011
6 · The paper itself

Abstract

The aim of this research was to evaluate the biologic potential of calcium phosphate (CaP) biopowders produced with a novel reaction synthesis system. Decomposition combustion synthesis (DCS) is a modified combustion synthesis method capable of producing CaP powders for use in bone tissue engineering applications. During DCS, the stoichiometric ratio of reactant salt to fuel was adjusted to alter product chemistry and morphology. In vitro testing methods were utilized to determine the effects of controlling product composition on cytotoxicity, proliferation, biocompatibility and biomineralization. In vitro, human fetal osteoblasts (ATCC, CRL-11372) cultured with CaP powder displayed a flattened morphology, and uniformly encompassed the CaP particulates. Matrix vesicles containing calcium and phosphorous budded from the osteoblast cells. CaP powders produced via DCS are a source of biologically active, synthetic, bone graft substitute materials.

Indexed as

BioactivityBone tissue engineeringCalcium phosphateDecomposition combustion synthesisOsteoblasts

Identifiers

PMID26034341
PMCPMC4448779

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.