Evidence map›Paper›PMID 26034340›Full record

ArticleTetrahedron letters2015

Copper-promoted synthesis of 1,4-benzodiazepinones via alkene diamination.

Shuklendu D Karyakarte, Fatima C Sequeira, Garrick H Zibreg, Guoqing Huang, Josiah P Matthew, Marina M M Ferreira, Sherry R Chemler

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tetrahedron letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Shuklendu D KaryakarteDepartment of Chemistry, State University of New York at Buffalo, Buffalo, New York 14260, USA, Tel: 716-645-4225;
Fatima C SequeiraDepartment of Chemistry, State University of New York at Buffalo, Buffalo, New York 14260, USA, Tel: 716-645-4225;
Garrick H ZibregDepartment of Chemistry, State University of New York at Buffalo, Buffalo, New York 14260, USA, Tel: 716-645-4225;
Guoqing HuangDepartment of Chemistry, State University of New York at Buffalo, Buffalo, New York 14260, USA, Tel: 716-645-4225;
Josiah P MatthewDepartment of Chemistry, State University of New York at Buffalo, Buffalo, New York 14260, USA, Tel: 716-645-4225;
Marina M M FerreiraDepartment of Chemistry, State University of New York at Buffalo, Buffalo, New York 14260, USA, Tel: 716-645-4225;
Sherry R ChemlerDepartment of Chemistry, State University of New York at Buffalo, Buffalo, New York 14260, USA, Tel: 716-645-4225;
University at Buffalo, State University of New York · US

Funding

New Methods for Nitrogen Heterocycle SynthesisR01GM078383 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI CHEMLER, SHERRY R · 2006 to 2023
$5.6M
NIGMS NIH HHS R01 GM078383
6 · The paper itself

Abstract

A new method for the synthesis of 2-aminomethyl functionalized 1,4-benzodiazepin-5-ones is presented. The benzodiazepine core is well-known to interact with biological receptors and many pharmaceutical drugs are derived from this structure. The alkene diamination strategy is employed for the first time for the synthesis of 1,4-benzodiazepinones. In this reaction, copper(2-ethylhexanoate)

Indexed as

1, 4-benzodiazepinonesalkenescopper-promoteddiamination

Identifiers

PMID26034340
PMCPMC4448762
OpenAlexW2039195522

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.