Evidence map›Paper›PMID 26034315›Full record

ReviewSingapore medical journal2015

Advances in the management of diabetic macular oedema based on evidence from the Diabetic Retinopathy Clinical Research Network.

Lik Thai Lim, Seen Nee Chia, Elliott Yann Ah-Kee, Nejia Chew, Manish Gupta

Open access · diamondAbstract readReview
In one paragraph

Review in Singapore medical journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lik Thai LimTennent Institute of Ophthalmology, Gartnavel General Hospital, Glasgow, Scotland, United Kingdom.
Seen Nee ChiaTennent Institute of Ophthalmology, Gartnavel General Hospital, Glasgow, Scotland, United Kingdom.
Elliott Yann Ah-KeeMonklands Hospital, Airdrie, North Lanarkshire, Scotland, United Kingdom.
Nejia ChewEye Department, Royal Victoria Infirmary, Newcastle upon Tyne, Tyne and Wear, England, United Kingdom.
Manish GuptaTennent Institute of Ophthalmology, Gartnavel General Hospital, Glasgow, Scotland, United Kingdom.
Gartnavel General Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Diabetic Retinopathy Clinical Research Network (DRCR.net) performs studies on new treatments for diabetic retinopathy. This review aims to summarise recent findings from DRCR.net studies on the treatment of diabetic macular oedema. We performed a PubMed search of articles from the DRCR.net, which included all studies pertaining to the treatment of diabetic maculopathy. The main outcome measures were retinal thickening as assessed by central subfield thickness on optical coherence tomography and improvement of visual acuity on the Early Treatment Diabetic Retinopathy Study (ETDRS) chart. Findings from each study were divided into modalities of treatment, namely photocoagulation, bevacizumab, triamcinolone, ranibizumab and vitrectomy. While modified ETDRS focal/grid laser remains the standard of care, intravitreal corticosteroids or anti-vascular endothelial growth factor agents have also proven to be effective, although they come with associated side effects. The choice of treatment modality for diabetic macular oedema is a clinical judgement call, and depends on the patient's clinical history and assessment.

Indexed as

Adrenal Cortex HormonesBevacizumabBiomedical ResearchDiabetic RetinopathyDisease ManagementDisease ProgressionHumansLight CoagulationMacular EdemaRanibizumabRetinaTomography, Optical CoherenceTriamcinoloneVascular Endothelial Growth Factor AVisual AcuityVitrectomyAdrenal Cortex HormonesBevacizumabRanibizumabTriamcinoloneVascular Endothelial Growth Factor Adiabetic macular oedemaDRCR.net reviewtreatment

Identifiers

PMID26034315
PMCPMC4447924
OpenAlexW643746643

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.