Evidence map›Paper›PMID 26033695›Full record

Observational studyThe Journal of infection2015

Tuberculosis-related knowledge is associated with patient outcomes in shantytown residents; results from a cohort study, Peru.

Emma E Westerlund, Marco A Tovar, Elisabet Lönnermark, Rosario Montoya, Carlton A Evans

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in The Journal of infection, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
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  6. Tuberculosis Scientific Conferences in Peru: Sharing local evidence for local decisions.Journal of clinical tuberculosis and other mycobacterial diseases · 2021
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  9. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Emma E WesterlundIFHAD: Innovation For Health And Development, Laboratory of Research and Development #218, Universidad Peruana Cayetano Heredia, San Martin de Porres, Lima, Peru; Department of Infectious Diseases, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Sweden.
Marco A TovarIFHAD: Innovation For Health And Development, Laboratory of Research and Development #218, Universidad Peruana Cayetano Heredia, San Martin de Porres, Lima, Peru; Innovacion Por la Salud Y el Desarollo (IPSYD), Asociación Benefica Prisma, Lima, Peru.
Elisabet LönnermarkDepartment of Infectious Diseases, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Sweden.
Rosario MontoyaInnovacion Por la Salud Y el Desarollo (IPSYD), Asociación Benefica Prisma, Lima, Peru.
Carlton A EvansIFHAD: Innovation For Health And Development, Laboratory of Research and Development #218, Universidad Peruana Cayetano Heredia, San Martin de Porres, Lima, Peru; Infectious Diseases & Immunity, Imperial College London, and Wellcome Trust Imperial College Centre for Global Health Research, London, UK. Electronic address: carlton.evans@ifhad.org.
Prisma · PEImperial College London · GBUniversidad Peruana Cayetano Heredia · PEUniversity of Gothenburg · SE

Funding

Medical Research Council MR/K007467/1Wellcome Trust 057434
6 · The paper itself

Abstract

objectivesTuberculosis is frequent among poor and marginalized people whose limited tuberculosis-related knowledge may impair healthcare access. We characterised tuberculosis-related knowledge and associations with delayed treatment and treatment outcome.

methodsTuberculosis patients (n = 943), people being tested for suspected tuberculosis (n = 2020), and randomly selected healthy controls (n = 476) in 16 periurban shantytowns were interviewed characterizing: socio-demographic factors; tuberculosis risk-factors; and patients' treatment delay. Principle component analysis was used to generate a tuberculosis-related knowledge score. Patients were followed-up for median 7.7 years. Factors associated with tuberculosis treatment delay, treatment outcome and tuberculosis recurrence were assessed using linear, logistic and Cox regression.

resultsTuberculosis-related knowledge was poor, especially in older people who had not completed schooling and had never been diagnosed with tuberculosis. Tuberculosis treatment delay was median 60 days and was more delayed for patients who were poorer, older, had more severe tuberculosis and in only unadjusted analysis with incomplete schooling and low tuberculosis-related knowledge (all p ≤ 0.03). Lower than median tuberculosis-related knowledge was associated with tuberculosis recurrence (unadjusted hazard ratio = 2.1, p = 0.008), and this association was independent of co-morbidities, disease severity and demographic factors (multiple regression adjusted hazard ratio = 2.6, p = 0.008).

conclusionsLow tuberculosis-related knowledge independently predicted tuberculosis recurrence. Thus health education may improve tuberculosis prognosis.

Indexed as

Health Knowledge, Attitudes, PracticePovertyAdultAge FactorsCohort StudiesFemaleFollow-Up StudiesHealth Services AccessibilityHumansMaleMultivariate AnalysisPatient Acceptance of Health CarePeruPrincipal Component AnalysisProportional Hazards ModelsRecurrenceClinical outcomeMycobacterium tuberculosisRecurrenceTuberculosis knowledge

Identifiers

PMID26033695
PMCPMC7617110
OpenAlexW1955737261

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.