Evidence map›Paper›PMID 26033685›Full record

ArticleGut and liver2015

IgG4-Associated Cholangitis Can Mimic Hilar Cholangiocarcinoma.

Victor M Zaydfudim, Andrew Y Wang, Eduard E de Lange, Zimin Zhao, Christopher A Moskaluk, Todd W Bauer, Reid B Adams

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Gut and liver, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Surgical management of biliary malignancy.Current problems in surgery · 2021
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. IgG4-associated sclerosing cholangitis masquerading as hilar cholangiocarcinoma.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2016
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Victor M ZaydfudimSection of Hepatobiliary and Pancreatic Surgery, Division of Surgical Oncology, USA.
Andrew Y WangDivision of Gastroenterology and Hepatology, USA.
Eduard E de LangeDepartment of Radiology and Medical Imaging, USA.
Zimin ZhaoDepartment of Pathology, University of Virginia, Charlottesville, VA, USA.
Christopher A MoskalukDepartment of Pathology, University of Virginia, Charlottesville, VA, USA.
Todd W BauerSection of Hepatobiliary and Pancreatic Surgery, Division of Surgical Oncology, USA.
Reid B AdamsSection of Hepatobiliary and Pancreatic Surgery, Division of Surgical Oncology, USA.
University of Virginia · USImaging Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IgG4-associated cholangitis can mimic hilar cholangiocarcinoma. Previously reported patients with IgG4-associated cholangitis mimicking cholangiocarcinoma had elevated serum IgG4 levels and long-segment biliary strictures. However, in the absence of other diagnostic criteria for malignancy, IgG4-associated cholangitis should remain a consideration among patients with normal serum IgG4 and a hilar mass suspicious for cholangiocarcinoma. The presence of a hilar mass and a malignant-appearing biliary stricture in two patients with normal serum IgG4 prompted further evaluation and subsequent concomitant liver and bile duct resection and reconstruction. The diagnosis of IgG4-associated cholangitis was established during the pathologic evaluation of the resected specimens. IgG4-associated cholangitis is a known imitator of hilar cholangiocarcinoma and should be considered in the differential diagnosis even among serologically IgG4-negative patients with a hilar mass prior to operative resection.

Indexed as

AgedBile DuctsCholangitisDiagnosis, DifferentialHumansImmunoglobulin GKlatskin TumorLiverMaleImmunoglobulin GAutoimmune cholangiopathyAutoimmune pancreatitisBiliary strictureHilar massIgG4 cholangiopathy

Identifiers

PMID26033685
PMCPMC4478001
OpenAlexW2172531616

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.